Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging

Xueqiu Jian , Claudia Satizabal , Albert Smith (1) , Katharina Wittfeld (2) , Joshua Bis , Jennifer Smith , Fang-Chi Hsu , Kwangsik Nho (3) , Edith Hofer (4) , Saskia Hagenaars (5) , Paul Nyquist (6) , Aniket Mishra , Hieab H.H. Adams (7) , Shuo Li (8) , Alexa Teumer , Wei Zhao (9) , Barry Freedman , Yasaman Saba , Lisa Yanek (10) , Ganesh Chauhan (11) , Mark van Buchem (12) , Mary Cushman , Natalie Royle , R. Nick Bryan , Wiro J. Niessen (13) , Beverly Windham , Anita Destefano (14) , Mohamad Habes (15) , Susan Heckbert , Nicholette Palmer , Cora Lewis , Gudny Eiriksdottir , Pauline Maillard (16) , Rasika Mathias , Georg Homuth (17) , Maria del C. Valdés-Hernández , Jasmin Divers , Alexa Beiser (18) , Sönke Langner , Kenneth Rice (19) , Mark Bastin (20) , Qiong Yang (21) , Joseph Maldjian , John Starr , Stephen Sidney , Shannon Risacher , Andre Uitterlinden (22) , Vilmundur Gudnason (23) , Matthias Nauck (24) , Jerome Rotter , Pamela Schreiner , Eric Boerwinkle (25) , Cornelia van Duijn (26) , Bernard Mazoyer (16) , Bettina von Sarnowski (27) , Rebecca Gottesman , Daniel Lévy (28) , Sigurdur Sigurdsson (29) , Meike Vernooij (30) , Stephen Turner , Reinhold Schmidt (30) , Joanna Wardlaw (20) , Bruce Psaty , Thomas Mosley , Charles Decarli (31) , Andrew Saykin (3) , Donald Bowden , Diane Becker , Ian J Deary (30) , Helena Schmidt (32) , Sharon L.R. Kardia , M. Arfan Arfan Ikram (30) , Stéphanie Debette (33) , Hans J Grabe (34) , W.T. Longstreth , Sudha Seshadri (30) , Lenore Launer , Myriam Fornage (25)

1 Plymouth University
2 Greifswald University Hospital
3 Indiana University School of Medicine
4 UGA UFR SHS - Université Grenoble Alpes - UFR Sciences de l'Homme et de la Société
5 Sans affiliation
6 Department of Neurology
7 Institut Gilbert-Laustriat : Biomolécules, Biotechnologie, Innovation Thérapeutique
8 Bruce E. Butler Laboratory
9 CAU - China Agricultural University
10 General Internal Medicine, Johns Hopkins School of Medicine
11 INSERM Research Center for Epidemiology and Biostatistics (U897) Team Neuroepidemiology, Bordeaux, France College of Health Sciences, University of Bordeaux, Bordeaux, France
12 Department of Radiology [Leiden, The Netherlands]
13 ISI - Image sciences institute - University of Utrecht
14 BU - Boston University [Boston]
15 Perelman School of Medicine
16 GIN - [GIN] Grenoble Institut des Neurosciences
17 Interfaculty Institute for Genetics and Functional Genomics
18 Neurology Department
19 University of Washington [Seattle]
20 Edin. - University of Edinburgh
21 University of Miami [Coral Gables]
22 Internal Medicine
23 Faculty of Medicine
24 Institute of Clinical Chemistry and Laboratory Medicine
25 UTHealth - The University of Texas Health Science Center at Houston
26 Erasmus MC - Erasmus University Medical Center [Rotterdam]
27 Dept of Neurology, Univ Medicine of Greifswald, Germany
28 PSE - Paris-Jourdan Sciences Economiques
29 Broad Institute [Cambridge]
30 Metacohorts Consortium
31 UCDavis-Neuro - Neurology Department, University of California, Davis
32 Department of Physics [Stockholm]
33 BPH - Bordeaux population health
34 Department of Psychiatry and Psychotherapy

Domaines: Neurosciences

Xueqiu Jian, Claudia Satizabal, Albert Smith, Katharina Wittfeld, Joshua Bis, et al.. Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging. Stroke, 2018, ⟨10.1161/STROKEAHA.118.020689⟩. ⟨hal-01868338⟩