Hyperkinetic motor seizures: a common semiology generated by two different cortical seizure origins

Lisa Vaugier (1) , Aileen Mcgonigal (2, 1) , Stanislas Lagarde (1, 2) , Agnès Trébuchon (2, 1) , William Szurhaj (3) , Philippe Derambure (3) , Fabrice Bartolomei (2, 1)

1 Service de neurophysiologie clinique [Hôpital de la Timone - APHM]
2 INS - Institut de Neurosciences des Systèmes
3 CHRU Lille - Service de neurophysiologie clinique

– We report a 37-year-old, right-handed patient with drug-resistant focal epilepsy whose seizures were characterized by explosive hyperkinetic behaviour. Video-SEEG revealed bifocal organization of epilepsy with two distinct cortical origins of seizures: the right temporal pole and left temporal lateral and perisylvian cortex. Irrespective of the cortical pattern of seizure onset, the hyperkinetic semiology was extremely similar. This supports a major role for " final common pathway " subcortical circuits in the genesis of the hyperkinetic semiology in this patient.

Mots clés: focal epilepsy; hyperkinetic / hypermotor semiology; central pattern generator

Domaines: Neurosciences

Lisa Vaugier, Aileen Mcgonigal, Stanislas Lagarde, Agnès Trébuchon, William Szurhaj, et al.. Hyperkinetic motor seizures: a common semiology generated by two different cortical seizure origins. Epileptic Disorders, 2018, 19 (3), pp.362 - 368. ⟨10.1684/epd.2017.0932⟩. ⟨hal-01851691⟩