Cantilever-based microsystem for contact and non-contact deposition of picoliter biological samples - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Sensors and Actuators A: Physical Année : 2004

Cantilever-based microsystem for contact and non-contact deposition of picoliter biological samples

Résumé

This paper describes a cantilever-based microsystem that permits the deposition of picoliter biological samples using a contact or non-contact method. Arrays of silicon-based cantilevers have been used to produce DNA microarrays. An electrowetting-on-dielectric (EWOD) principle is applied for the loading of the liquid by controlling surface tension. Deposition is achieved by direct contact between cantilevers and the surface by capillary transport. A non-contact deposition method has also been developed. It consists in an electric-field applied between the cantilevers and a conductive surface. The results obtained demonstrate that our system meets the need for producing high-density DNA, protein and cell chips.
Fichier principal
Vignette du fichier
1-s2.0-S0924424703004722-main(1).pdf (393.77 Ko) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Loading...

Dates et versions

hal-01849255 , version 1 (05-06-2019)

Identifiants

Citer

Pascal Belaubre, Matthieu Guirardel, Véronique Le Berre, Jean Bernard Pourciel, Christian Bergaud. Cantilever-based microsystem for contact and non-contact deposition of picoliter biological samples. Sensors and Actuators A: Physical , 2004, 110 (1-3), pp.130 - 135. ⟨10.1016/j.sna.2003.09.024⟩. ⟨hal-01849255⟩
136 Consultations
115 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More