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Le donneur vivant de rein

Abstract : OBJECTIVES: To review ethical, legal and technical aspects of living kidney donor surgery. MATERIAL AND METHODS: An exhaustive systematic review of the scientific literature was performed in the Medline database (http://www.ncbi.nlm.nih.gov) and Embase (http://www.embase.com) using different associations of the following keywords: Donor nephrectomy; Kidney paired donation; Kidney transplantation; Laparoscopic nephrectomy; Living donor; Organs trafficking; Robotic assisted nephrectomy; Vaginal extraction. French legal documents have been reviewed using the government portal (http://www.legifrance.gouv.fr). Articles were selected according to methods, language of publication and relevance. A total of 6421 articles were identified; after careful selection, 161 publications were considered of interest and were eligible for our review. RESULTS: The ethical debate focuses on organ shortage, financial incentive, organ trafficking and the recent data suggesting a small but significant increase risk for late renal disease in donor population. Legal decisions aim to increase the number of kidneys available for donation, such as kidney-paired donation that faces several obstacles in France. Laparoscopic approach became widely used, while robotic-assisted donor nephrectomy failed to demonstrate improved outcome as compared with other minimal invasive techniques. CONCLUSION: Minimally invasive living donor nephrectomy aims to limit side effects in the donor without increasing the morbidity in this specific population of healthy persons; long term surveillance to prevent the onset of renal disease in mandatory.
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https://hal.archives-ouvertes.fr/hal-01818678
Contributor : Anthony Herrada <>
Submitted on : Tuesday, June 19, 2018 - 1:56:52 PM
Last modification on : Thursday, May 27, 2021 - 5:08:03 PM

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M.-O. Timsit, F. Kleinclauss, M.F. Mamzer Bruneel, R. Thuret. Le donneur vivant de rein. Progrès en Urologie, Elsevier Masson, 2016, 26 (15), pp.940 - 963. ⟨10.1016/j.purol.2016.09.054⟩. ⟨hal-01818678⟩

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