Organic-inorganic composites for bone substitute and bone repair applications: concepts, first results and potentialities

Marianna Peroglio (1) , Nathalie Ginsac (1) , Jérome Chevalier (1) , Laurent Gremillard (1) , Sylvain Meille (1) , Laurent Chazeau (1) , Catherine Gauthier (1) , J.-M. Chenal (1)

1 MATEIS - Matériaux, ingénierie et science [Villeurbanne]

Here we show a brief outline of organic-inorganic composites for bone substitute and bone repair applications. Two types of composites are presented. In a first strategy, porous ceramics and bioactive glasses processed by sintering methods are impregnated by a polymer. The strong improvement of the mechanical properties of the ceramic scaffolds by a polymer phase can be linked to the one present in bone with the role of collagen on bone toughness. In a second strategy, a bioresorbable polymer and an osteo-inductive glass-ceramic in the form of fillers are chosen to process bone repair devices by polymer technologies (injection). The two examples presented show that architecture, multi-functional inorganic-organic composites can be processed for the development of devices able to improve bone regeneration processes.

Domaines: Matériaux

Marianna Peroglio, Nathalie Ginsac, Jérome Chevalier, Laurent Gremillard, Sylvain Meille, et al.. Organic-inorganic composites for bone substitute and bone repair applications: concepts, first results and potentialities. JA 2013 - JOURNEES ANNUELLES DE LA SF2M 2013 / SF2M ANNUAL MEETING 2013, 2013, 17 AVE DU HOGGAR PARC D ACTIVITES COUTABOEUF BP 112, F-91944 CEDEX A, France. ⟨10.1051/matecconf/20130704013⟩. ⟨hal-01814439⟩