How a Glycoside Hydrolase Recognizes a Helical Polyglucan

How a Glycoside Hydrolase Recognizes a Helical Polyglucan.

Bernard Henrissat (1) , Marie-Line Garron (1)

1 AFMB - Architecture et fonction des macromolécules biologiques

Similarly to other biopolymers, linear polysaccharides can form double- or triple-helical structures. How enzymes recognize and manage this quaternary structure is an unresolved question. In this issue of Structure, Pluvinage et al. (2017) shed light on the structural complementarity between family GH81 glycoside hydrolase and the quaternary structure of their polysaccharide substrates.

Domaines: Biologie structurale [q-bio.BM]; Biochimie [q-bio.BM]; Biotechnologies; Bio-Informatique, Biologie Systémique [q-bio.QM]; Bactériologie; Virologie; Neurobiologie; Pharmacologie; Maladies émergentes; Maladies infectieuses; Immunité innée

Bernard Henrissat, Marie-Line Garron. How a Glycoside Hydrolase Recognizes a Helical Polyglucan. Structure, 2017, 25 (9), pp.1319 - 1321. ⟨10.1016/j.str.2017.08.004⟩. ⟨hal-01802859⟩