Escherichia coli spontaneous community-acquired meningitis in adults: A case report and literature review

A. Bichon (1) , C. Aubry (1) , G. Dubourg (2, 1) , H. Drouet (1) , J. -C. Lagier (2, 1) , Didier Raoult (2, 1) , Philippe Parola (3, 1)

1 URMITE - Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes
2 MEPHI - Microbes évolution phylogénie et infections
3 VITROME - Vecteurs - Infections tropicales et méditerranéennes

Gram-negative bacillary meningitis occurring post-trauma and following neurosurgical procedures has been described widely. However, reports of spontaneous cases are sparse, particularly communityacquired cases. Spontaneous community-acquired Escherichia coli meningitis is a rare (although increasingly seen) and specific entity that is poorly reported in the literature. A review of the literature identified only 43 cases of community-acquired E. coli meningitis reported between 1946 and 2016. This article describes two new cases of spontaneous community-acquired E. coli meningitis encountered in Marseille, France, and presents the results of a literature review on spontaneous community-acquired E. coli meningitis.

Mots clés: Escherichia coli; Gram-negatiive meningitis; Spontaneous community-acquired

Domaines: Maladies infectieuses

A. Bichon, C. Aubry, G. Dubourg, H. Drouet, J. -C. Lagier, et al.. Escherichia coli spontaneous community-acquired meningitis in adults: A case report and literature review. International Journal of Infectious Diseases, 2018, 67, pp.70-74. ⟨10.1016/j.ijid.2017.12.003⟩. ⟨hal-01780648⟩