Dynamics of Ebola RNA Persistence in Semen: A Report From the Postebogui Cohort in Guinea

Fabien Subtil (1, 2, 3, 4, 5) , Charlotte Delaunay (1, 2, 4) , Alpha Kabinet Keita (1) , Mamadou Saliou Sow , Abdoulaye Touré (1) , Sandrine Leroy (1) , Philippe Msellati (1) , N'Fally Magassouba , Sylvain Baize (6) , Hervé Raoul (7) , René Ecochard (2, 3) , Moumié Barry , Eric Delaporte (1) , Jean-François Etard (1) , Postebogui Study Group

1 TransVIHMI - Recherches Translationnelles sur le VIH et les maladies infectieuses endémiques et émergentes
2 Service de Biostatistiques [Lyon]
3 Biostatistiques santé
4 LBBE - Laboratoire de Biométrie et Biologie Evolutive - UMR 5558
5 HCL - Hospices Civils de Lyon
6 UBIVE - Biologie des Infections Virales Émergentes - Biology of Emerging Viral Infections
7 Unité de service 3 - Laboratoire P4 Jean Mérieux-Inserm [Lyon]

This study modeled the presence of Ebola virus RNA in the semen of male Ebola survivors participating in the Postebogui study in Guinea. The median time of reverse-transcription polymerase chain reaction negativity was 46.4 days after symptom onset (95% confidence interval, 11-82.6). The results emphasize the importance of the World Health Organization recommendations for survivors' management.

Mots clés: Guinea; Ebola; PCR.; sexual transmission; semen

Domaines: Immunologie; Maladies infectieuses; Microbiologie et Parasitologie

Fabien Subtil, Charlotte Delaunay, Alpha Kabinet Keita, Mamadou Saliou Sow, Abdoulaye Touré, et al.. Dynamics of Ebola RNA Persistence in Semen: A Report From the Postebogui Cohort in Guinea. Clinical Infectious Diseases, 2017, 64 (12), pp.1788 - 1790. ⟨10.1093/cid/cix210⟩. ⟨hal-01773727⟩