M. Stanbrough, D. W. Rowen, and B. Magasanik, Role of the GATA factors Gln3p and Nil1p of Saccharomyces cerevisiae in the expression of nitrogen-regulated genes., Proceedings of the National Academy of Sciences, vol.92, issue.21, pp.9450-9454, 1995.
DOI : 10.1073/pnas.92.21.9450

J. A. Coffman, R. Rai, T. Cunningham, V. Svetlov, C. et al., Gat1p, a GATA family protein whose production is sensitive to nitrogen catabolite repression, participates in transcriptional activation of nitrogen-catabolic genes in Saccharomyces cerevisiae., Molecular and Cellular Biology, vol.16, issue.3, pp.847-858, 1996.
DOI : 10.1128/MCB.16.3.847

P. O. Ljungdahl, C. J. Gimeno, C. A. Styles, and G. R. Fink, SHR3: A novel component of the secretory pathway specifically required for localization of amino acid permeases in yeast, Cell, vol.71, issue.3, pp.463-478, 1992.
DOI : 10.1016/0092-8674(92)90515-E

M. J. Kuehn, R. Schekman, and P. O. Ljungdahl, Amino acid permeases require COPII components and the ER resident membrane protein Shr3p for packaging into transport vesicles in vitro, The Journal of Cell Biology, vol.135, issue.3, pp.585-595, 1996.
DOI : 10.1083/jcb.135.3.585

M. J. Kuehn, J. M. Herrmann, and R. Schekman, COPII???cargo interactions direct protein sorting into ER-derived transport vesicles, Nature, vol.5, issue.6663, pp.187-190, 1998.
DOI : 10.1128/MCB.5.12.3610

C. F. Gilstring, M. Melin-larsson, and P. O. Ljungdahl, Shr3p Mediates Specific COPII Coatomer-Cargo Interactions Required for the Packaging of Amino Acid Permeases Into ER-derived Transport Vesicles, Molecular Biology of the Cell, vol.10, issue.11, pp.3549-3565, 1999.
DOI : 10.1091/mbc.10.11.3549

P. Novick, S. Ferro, and R. Schekman, Order of events in the yeast secretory pathway, Cell, vol.25, issue.2, pp.461-469, 1981.
DOI : 10.1016/0092-8674(81)90064-7

C. A. Kaiser and R. Schekman, Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway, Cell, vol.61, issue.4, pp.723-733, 1990.
DOI : 10.1016/0092-8674(90)90483-U

N. K. Pryer, N. R. Salama, R. Schekman, K. , and C. A. , Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro, The Journal of Cell Biology, vol.120, issue.4, pp.865-875, 1993.
DOI : 10.1083/jcb.120.4.865

C. Barlowe, L. Orci, T. Yeung, M. Hosobuchi, S. Hamamoto et al., COPII: A membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum, Cell, vol.77, issue.6, pp.895-907, 1994.
DOI : 10.1016/0092-8674(94)90138-4

W. Guo, M. Sacher, J. Barrowman, S. Ferro-novick, and P. Novick, Protein complexes in transport vesicle targeting, Trends in Cell Biology, vol.10, issue.6, pp.251-255, 2000.
DOI : 10.1016/S0962-8924(00)01754-2

K. A. Becherer, S. E. Rieder, S. D. Emr, and E. W. Jones, Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the lysosome-like vacuole in yeast., Molecular Biology of the Cell, vol.7, issue.4, pp.579-594, 1996.
DOI : 10.1091/mbc.7.4.579

M. Grenson, Inactivation-Reactivation Process and Repression of Permease Formation Regulate Several Ammonia-Sensitive Permeases in the Yeast Saccharomyces cerevisiae, European Journal of Biochemistry, vol.94, issue.1, pp.135-139, 1983.
DOI : 10.1016/0304-4165(66)90387-4

J. C. Jauniaux and M. Grenson, GAP1, the general amino acid permease gene of Saccharomyces cerevisiae. Nucleotide sequence, protein similarity with the other bakers yeast amino acid permeases, and nitrogen catabolite repression, European Journal of Biochemistry, vol.157, issue.1, pp.39-44, 1990.
DOI : 10.1146/annurev.biochem.54.1.631

C. Hein, J. Y. Springael, C. Volland, R. Haguenauer-tsapis, and B. André, NPI1, an essential yeast gene involved in induced degradation of Gap1 and Fur4 permeases, encodes the Rsp5 ubiquitin-protein ligase, Molecular Microbiology, vol.18, issue.1, pp.77-87, 1995.
DOI : 10.1111/j.1365-2958.1995.mmi_18010077.x

J. Y. Springael and B. André, Nitrogen-regulated Ubiquitination of the Gap1 Permease of Saccharomyces cerevisiae, Molecular Biology of the Cell, vol.9, issue.6, pp.1253-1263, 1998.
DOI : 10.1091/mbc.9.6.1253

M. Hochstrasser, UBIQUITIN-DEPENDENT PROTEIN DEGRADATION, Annual Review of Genetics, vol.30, issue.1, pp.405-439, 1996.
DOI : 10.1146/annurev.genet.30.1.405

L. Hicke, Gettin??? down with ubiquitin: turning off cell-surface receptors, transporters and channels, Trends in Cell Biology, vol.9, issue.3, pp.107-112, 1999.
DOI : 10.1016/S0962-8924(98)01491-3

J. M. Huibregtse, M. Scheffner, S. Beaudenon, and P. M. Howley, A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase., Proceedings of the National Academy of Sciences, vol.92, issue.7, pp.2563-2567, 1995.
DOI : 10.1073/pnas.92.7.2563

M. Vandenbol, J. C. Jauniaux, and M. Grenson, TheSaccharomyces cerevisiae NPR1 gene required for the activity of ammonia-sensitive amino acid permeases encodes a protein kinase homologue, MGG Molecular & General Genetics, vol.28, issue.2-3, pp.393-399, 1990.
DOI : 10.1007/BF00633845

E. Dubois and M. Grenson, Methylamine/ammonia uptake systems in Saccharomyces cerevisiae: multiplicity and regulation, MGG Molecular & General Genetics, vol.248, issue.1, pp.67-76, 1979.
DOI : 10.1007/BF00267857

M. Grenson, Study of the Positive Control of the General Amino-Acid Permease and Other Ammonia-Sensitive Uptake Systems by the Product of the NPR1 Gene in the Yeast Saccharomyces cerevisiae, European Journal of Biochemistry, vol.196, issue.1, pp.141-144, 1983.
DOI : 10.1042/bj1960531

R. Rai, F. S. Genbauffe, C. , and T. G. , Structure and transcription of the allantoate permease gene (DAL5) from Saccharomyces cerevisiae., Journal of Bacteriology, vol.170, issue.1, pp.266-271, 1988.
DOI : 10.1128/jb.170.1.266-271.1988

M. Vandenbol, J. C. Jauniaux, S. Vissers, and M. Grenson, Isolation of the NPRI gene responsible for the reactivatiion of ammonia-sensitive amino-acid permeases in Saccharomyces cerevisiae. RNA analysis and gene dosage effects, European Journal of Biochemistry, vol.12, issue.3, pp.607-612, 1987.
DOI : 10.1007/BF00267295

T. Hunter and G. D. Plowman, The protein kinases of budding yeast: six score and more, Trends in Biochemical Sciences, vol.22, issue.1, pp.18-22, 1997.
DOI : 10.1016/S0968-0004(96)10068-2

M. Kaouass, M. Audette, D. Ramotar, S. Verma, D. De-montigny et al., The STK2 gene, which encodes a putative Ser/Thr protein kinase, is required for high-affinity spermidine transport in Saccharomyces cerevisiae., Molecular and Cellular Biology, vol.17, issue.6, pp.2994-3004, 1997.
DOI : 10.1128/MCB.17.6.2994

J. M. Mulet, M. P. Leube, S. J. Kron, G. Rios, G. R. Fink et al., A Novel Mechanism of Ion Homeostasis and Salt Tolerance in Yeast: the Hal4 and Hal5 Protein Kinases Modulate the Trk1-Trk2 Potassium Transporter, Molecular and Cellular Biology, vol.19, issue.5, pp.3328-3337, 1999.
DOI : 10.1128/MCB.19.5.3328

C. Hein and B. André, -induced inactivation and degradation of the general amino acid permease, Gap1p, of Saccharomyces cerevisiae, Molecular Microbiology, vol.24, issue.3, pp.607-616, 1997.
DOI : 10.1046/j.1365-2958.1997.3771735.x

A. Schmidt, T. Beck, A. Koller, J. Kunz, and M. N. Hall, The TOR nutrient signalling pathway phosphorylates NPR1 and inhibits turnover of the tryptophan permease, The EMBO Journal, vol.82, issue.23, pp.6924-6931, 1998.
DOI : 10.1016/0092-8674(95)90058-6

T. Beck, A. Schmidt, and M. N. Hall, Starvation Induces Vacuolar Targeting and Degradation of the Tryptophan Permease in Yeast, The Journal of Cell Biology, vol.164, issue.6, pp.1227-1238, 1999.
DOI : 10.1016/0092-8674(95)90058-6

J. Béchet, M. Grenson, and J. M. Wiame, Mutations Affecting the Repressibility of Arginine Biosynthetic Enzymes in Sacchromyces cerevisiae, European Journal of Biochemistry, vol.20, issue.1, pp.31-39, 1970.
DOI : 10.1042/bj0820489

P. Jacobs, J. C. Jauniaux, and M. Grenson, A cis-dominant regulatory mutation linked to the argB-argC gene cluster in Saccharomyces cerevisiae, Journal of Molecular Biology, vol.139, issue.4, pp.691-704, 1980.
DOI : 10.1016/0022-2836(80)90055-8

M. Grenson, Multiplicity of the amino acid permeases in Saccharomyces cerevisiae, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.127, issue.2, pp.339-346, 1966.
DOI : 10.1016/0304-4165(66)90388-6

H. Schä-gger, V. Jagow, and G. , Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa, Analytical Biochemistry, vol.166, issue.2, pp.368-379, 1987.
DOI : 10.1016/0003-2697(87)90587-2

U. K. Laemmli, Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4, Nature, vol.244, issue.5259, pp.680-685, 1970.
DOI : 10.1101/SQB.1963.028.01.053

D. Gietz, A. St-jean, R. A. Woods, and R. H. Schiestl, Improved method for high efficiency transformation of intact yeast cells, Nucleic Acids Research, vol.20, issue.6, p.1425, 1992.
DOI : 10.1093/nar/20.6.1425

G. S. Zubenko, F. J. Park, and E. W. Jones, Mutations in PEP4 locus of Saccharomyces cerevisiae block final step in maturation of two vacuolar hydrolases., Proceedings of the National Academy of Sciences, vol.80, issue.2, pp.510-514, 1983.
DOI : 10.1073/pnas.80.2.510

P. Novick, C. Field, and R. Schekman, Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway, Cell, vol.21, issue.1, pp.205-215, 1980.
DOI : 10.1016/0092-8674(80)90128-2

A. Salminen and P. J. Novick, A ras-like protein is required for a post-Golgi event in yeast secretion, Cell, vol.49, issue.4, pp.527-538, 1987.
DOI : 10.1016/0092-8674(87)90455-7

J. C. Holthuis, B. J. Nichols, S. Dhruvakumar, and H. R. Pelham, Two syntaxin homologues in the TGN/endosomal system of yeast, The EMBO Journal, vol.17, issue.1, pp.113-126, 1998.
DOI : 10.1093/emboj/17.1.113

O. Soetens, J. O. De-craene, and B. André, Ubiquitin Is Required for Sorting to the Vacuole of the Yeast General Amino Acid Permease, Gap1, Journal of Biological Chemistry, vol.133, issue.47, pp.43949-43957, 2001.
DOI : 10.1111/j.1432-1033.1983.tb07438.x
URL : https://hal.archives-ouvertes.fr/hal-01771881

S. B. Helliwell, S. Losko, K. , and C. A. , Components of a Ubiquitin Ligase Complex Specify Polyubiquitination and Intracellular Trafficking of the General Amino Acid Permease, The Journal of Cell Biology, vol.16, issue.4, pp.649-662, 2001.
DOI : 10.1016/S0378-1119(98)00535-6

M. J. Lewis, B. J. Nichols, C. Prescianotto-baschong, H. Riezman, and H. R. Pelham, Specific Retrieval of the Exocytic SNARE Snc1p from Early Yeast Endosomes, Molecular Biology of the Cell, vol.11, issue.1, pp.23-38, 2000.
DOI : 10.1091/mbc.11.1.23

B. Pinson, X. Pillois, D. Brethes, J. Chevallier, and C. Napias, In vivo Phosphorylation of the Purine/Cytosine Permease from the Plasma Membrane of the Yeast Saccharomyces cerevisiae, European Journal of Biochemistry, vol.8, issue.2, pp.439-444, 1996.
DOI : 10.1016/0076-6879(91)00125-G

A. Goossens, N. De-la-fuente, J. Forment, R. Serrano, and F. Portillo, Regulation of Yeast H+-ATPase by Protein Kinases Belonging to a Family Dedicated to Activation of Plasma Membrane Transporters, Molecular and Cellular Biology, vol.20, issue.20, pp.7654-7661, 2000.
DOI : 10.1128/MCB.20.20.7654-7661.2000

D. Rotin, O. Staub, and R. Haguenauer-tsapis, Ubiquitination and Endocytosis of Plasma Membrane Proteins: Role of Nedd4/Rsp5p Family of Ubiquitin-Protein Ligases, Journal of Membrane Biology, vol.176, issue.1, pp.1-17, 2000.
DOI : 10.1007/s00232001079

N. De-la-fuente, A. M. Maldonado, and F. Portillo, -ATPase requires the ubiquitin-proteasome proteolytic pathway, FEBS Letters, vol.269, issue.2-3, pp.308-312, 1997.
DOI : 10.1083/jcb.115.2.289

M. Grenson and B. Acheroy, Mutations affecting the activity and the regulation of the general amino-acid permease of Saccharomyces cerevisiae, MGG Molecular & General Genetics, vol.192, issue.2, pp.261-265, 1982.
DOI : 10.1007/BF00332685

D. Shortle, P. Novick, and D. Botstein, Construction and genetic characterization of temperature-sensitive mutant alleles of the yeast actin gene., Proceedings of the National Academy of Sciences, vol.81, issue.15, pp.4889-4893, 1984.
DOI : 10.1073/pnas.81.15.4889