Preparation and characterization of carnauba wax nanostructured lipid carriers containing benzophenone-3

Abstract : Nanostructured lipid carriers (NLCs) are potential active delivery systems based on mixtures of solid lipids and liquid oil. In this paper, aqueous dispersions of NLCs were prepared by a hot high-pressure homogenization technique using carnauba wax as the solid lipid and isodecyl oleate as the liquid oil. The preparation and stability parameters of benzophenone-3-loaded NLCs have been investigated concerning particle size, zeta potential and loading capacity to encapsulate benzophenone-3, a molecular sunscreen. The current investigation illustrates the effect of the composition of the lipid mixture on the entrapment efficiency, in vitro release and stability of benzophenone-3-loaded in these NLCs. A loading capacity of approximately 5% of benzophenone-3 (m(BZ-3)/m(lipids)) was characteristic of these systems.
Complete list of metadatas

Cited literature [32 references]  Display  Hide  Download

https://hal.archives-ouvertes.fr/hal-01717486
Contributor : Imt Mines Albi Ecole Nationale Supérieure Des Mines d'Albi-Carmaux <>
Submitted on : Monday, May 28, 2018 - 10:51:55 AM
Last modification on : Wednesday, September 19, 2018 - 9:26:55 AM
Long-term archiving on : Monday, September 24, 2018 - 4:56:16 PM

File

Lacerda_et_al-2011-Internation...
Publisher files allowed on an open archive

Identifiers

Collections

Citation

S. P. Lacerda, N. N. P. Cerize, Maria Inês Ré. Preparation and characterization of carnauba wax nanostructured lipid carriers containing benzophenone-3. International Journal of Cosmetic Science, Wiley, 2011, 33 (4), pp.312-321. ⟨10.1111/j.1468-2494.2010.00626.x⟩. ⟨hal-01717486⟩

Share

Metrics

Record views

85

Files downloads

214