Photoactivation of iron nanoparticles for the improvement of glioma treatment

Abstract : Rationale An alternative approach for the improvement of radiotherapy consists in increasing differentially the radiation dose between tumors and normal tissues using nanoparticles (NPs) that have been beforehand internalized into the tumor. These high-Z NPs can be photo-activated by monochromatic synchrotron X-rays, leading to a local dose enhancement delivered to the neighbouring tumor cells. In this study, we evaluated the ability of iron NPs to act as radiosensitizers in vitro and through simulations.
Type de document :
Communication dans un congrès
ARGENT - MSCA ITN - Advanced Radiotherapy, Generated by Exploiting Nanoprocesses and Technologies, Jan 2018, Paris, France. 2017
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https://hal.archives-ouvertes.fr/hal-01714444
Contributeur : Béatrice Rayet <>
Soumis le : mercredi 21 février 2018 - 15:07:23
Dernière modification le : vendredi 9 mars 2018 - 16:36:02

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  • HAL Id : hal-01714444, version 1

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Solveig Reymond, Paul Gimenez, Mélanie Flaender, Rachel Delorme, C. Bissardon, et al.. Photoactivation of iron nanoparticles for the improvement of glioma treatment. ARGENT - MSCA ITN - Advanced Radiotherapy, Generated by Exploiting Nanoprocesses and Technologies, Jan 2018, Paris, France. 2017. 〈hal-01714444〉

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