NOVEL 7-DEACETOXY BACCATINE IV DERIVATIVE, AND PREPARATION AND USE THEREOF

NOUVEAU DERIVE DE LA 7-DESACETOXY BACCATINE IV, SA PREPARATION ET SON EMPLOI

Alain Ahond (1) , Laurent Ettouati (1) , Pierre Potier (1) , Christiane Poupat (1)

1 CNRS - Centre National de la Recherche Scientifique

A novel 7-deacetoxy baccatine IV derivative having formula (I), the preparation thereof from taxine B, and its use in preparing biologically active products, are described. In said formula (I), R is a hydrogen atom or acetyl radical and R1, R2, R3, and R4 are hydroxy-function protective groupings (preferably acetonides).

Domaines: Médicaments; Chimie thérapeutique

Alain Ahond, Laurent Ettouati, Pierre Potier, Christiane Poupat. NOUVEAU DERIVE DE LA 7-DESACETOXY BACCATINE IV, SA PREPARATION ET SON EMPLOI. France, N° de brevet: WO 93/02064. 1993. ⟨hal-01709113⟩