K. Goslin and G. Banker, Experimental observations on the development of polarity by hippocampal neurons in culture, The Journal of Cell Biology, vol.108, issue.4, pp.1507-1516, 1989.
DOI : 10.1083/jcb.108.4.1507

K. L. Hedstrom, X. Xu, Y. Ogawa, R. Frischknecht, C. I. Seidenbecher et al., Neurofascin assembles a specialized extracellular matrix at the axon initial segment, The Journal of Cell Biology, vol.19, issue.5, pp.875-886, 2007.
DOI : 10.1083/jcb.143.5.1295

S. M. Jenkins and V. Bennett, Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments, The Journal of Cell Biology, vol.143, issue.5, pp.739-746, 2001.
DOI : 10.1083/jcb.143.5.1295

N. John, H. Krugel, R. Frischknecht, K. H. Smalla, C. Schultz et al., Brevican-containing perineuronal nets of extracellular matrix in dissociated hippocampal primary cultures, Molecular and Cellular Neuroscience, vol.31, issue.4, pp.774-784, 2006.
DOI : 10.1016/j.mcn.2006.01.011

M. H. Kole, S. U. Ilschner, B. M. Kampa, S. R. Williams, P. C. Ruben et al., Action potential generation requires a high sodium channel density in the axon initial segment, Nature Neuroscience, vol.26, issue.2, pp.178-186, 2008.
DOI : 10.1113/jphysiol.1982.sp014296

E. Kordeli, J. Davis, B. Trapp, and V. Bennett, An isoform of ankyrin is localized at nodes of Ranvier in myelinated axons of central and peripheral nerves, The Journal of Cell Biology, vol.110, issue.4, pp.1341-1352, 1990.
DOI : 10.1083/jcb.110.4.1341

E. Kordeli, S. Lambert, and V. Bennett, Ankyrin, Journal of Biological Chemistry, vol.268, issue.5, pp.2352-2359, 1995.
DOI : 10.1126/science.1439806

URL : https://hal.archives-ouvertes.fr/hal-00005407

S. Lambert, J. Q. Davis, and V. Bennett, Morphogenesis of the Node of Ranvier: Co-Clusters of Ankyrin and Ankyrin-Binding Integral Proteins Define Early Developmental Intermediates, The Journal of Neuroscience, vol.17, issue.18, pp.7025-7036, 1997.
DOI : 10.1523/JNEUROSCI.17-18-07025.1997

G. Lemaillet, S. Walker, and . Lambert, Identifi cation of a conserved ankyrin-binding motif in the family of sodium channel alpha subunits, 2003.

S. T. Lim, D. E. Antonucci, R. H. Scannevin, and J. S. Trimmer, A Novel Targeting Signal for Proximal Clustering of the Kv2.1 K+ Channel in Hippocampal Neurons, Neuron, vol.25, issue.2, pp.385-397, 2000.
DOI : 10.1016/S0896-6273(00)80902-2

J. Y. Lou, F. Laezza, B. R. Gerber, M. Xiao, K. A. Yamada et al., Fibroblast growth factor 14 is an intracellular modulator of voltage-gated sodium channels, The Journal of Physiology, vol.24, issue.1, 2005.
DOI : 10.1523/JNEUROSCI.1628-04.2004

P. M. Martin, M. Carnaud, G. Garcia-del-ca-Ñ-o, M. Irondelle, T. Irinopoulou et al., Schwannomin-Interacting Protein-1 Isoform IQCJ-SCHIP-1 Is a Late Component of Nodes of Ranvier and Axon Initial Segments, Journal of Neuroscience, vol.28, issue.24, pp.6111-6117, 2008.
DOI : 10.1523/JNEUROSCI.1044-08.2008

F. Meggio and L. A. Pinna, One-thousand-and-one substrates of protein kinase CK2?, The FASEB Journal, vol.17, issue.3, pp.349-368, 2003.
DOI : 10.1016/S0955-0674(00)00189-7

H. Misonou, M. Menegola, D. P. Mohapatra, L. K. Guy, K. S. Park et al., Bidirectional Activity-Dependent Regulation of Neuronal Ion Channel Phosphorylation, Journal of Neuroscience, vol.26, issue.52, pp.13505-13514, 2006.
DOI : 10.1523/JNEUROSCI.3970-06.2006

Y. Ogawa, D. P. Schafer, I. Horresh, V. Bar, K. Hales et al., Spectrins and AnkyrinB Constitute a Specialized Paranodal Cytoskeleton, Journal of Neuroscience, vol.26, issue.19, pp.5230-5239, 2006.
DOI : 10.1523/JNEUROSCI.0425-06.2006

Z. Pan, T. Kao, Z. Horvath, J. Lemos, J. Y. Sul et al., A Common Ankyrin-G-Based Mechanism Retains KCNQ and NaV Channels at Electrically Active Domains of the Axon, Journal of Neuroscience, vol.26, issue.10, pp.2599-2613, 2006.
DOI : 10.1523/JNEUROSCI.4314-05.2006

M. A. Pagano, F. Meggio, M. Ruzzene, M. Andrzejewska, Z. Kazimierczuk et al., 2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2, Biochemical and Biophysical Research Communications, vol.321, issue.4, pp.1040-1044, 2004.
DOI : 10.1016/j.bbrc.2004.07.067

K. S. Park, D. P. Mohapatra, H. Misonou, and J. S. Trimmer, Graded Regulation of the Kv2.1 Potassium Channel by Variable Phosphorylation, Science, vol.313, issue.5789, pp.976-979, 2006.
DOI : 10.1126/science.1124254

C. Politi, D. Del-turco, J. M. Sie, P. A. Golinski, I. Tegeder et al., Accumulation of phosphorylated IkappaBalpha and activated IKK in nodes of Ranvier, Neuropathol. Appl. Neurobiol, vol.313, pp.976-979, 2007.

R. L. Rich and D. G. Myszka, Survey of the year 2006 commercial optical biosensor literature, Journal of Molecular Recognition, vol.39, issue.574, pp.300-366, 2007.
DOI : 10.13031/2013.21709

J. L. Salzer, Polarized Domains of Myelinated Axons, Neuron, vol.40, issue.2, pp.297-318, 2003.
DOI : 10.1016/S0896-6273(03)00628-7

C. Schultz, H. G. Konig, D. Del-turco, C. Politi, G. P. Eckert et al., Coincident enrichment of phosphorylated I??B??, activated IKK, and phosphorylated p65 in the axon initial segment of neurons, Molecular and Cellular Neuroscience, vol.33, issue.1, pp.68-80, 2006.
DOI : 10.1016/j.mcn.2006.06.008

Y. Srinivasan, M. Lewallen, and K. J. Angelides, Mapping the binding site on ankyrin for the voltage-dependent sodium channel from brain, J. Biol. Chem, vol.267, pp.7483-7489, 1992.

K. M. Abdi, P. J. Mohler, J. Q. Davis, and V. Bennett, Isoform Specificity of Ankyrin-B, Journal of Biological Chemistry, vol.236, issue.9, pp.5741-5749, 2006.
DOI : 10.1083/jcb.137.3.703

N. Alessandri-haber, C. Paillart, C. Arsac, M. Gola, F. Couraud et al., Specific distribution of sodium channels in axons of rat embryo spinal motoneurones, The Journal of Physiology, vol.128, issue.1, pp.203-214, 1999.
DOI : 10.1016/0012-1606(88)90262-X

S. Basak, K. Raju, J. Babiarz, N. Kane-goldsmith, D. Koticha et al., Differential expression and functions of neuronal and glial neurofascin isoforms and splice variants during PNS development, Developmental Biology, vol.311, issue.2, pp.408-422, 2007.
DOI : 10.1016/j.ydbio.2007.08.045

V. Bennett and S. Lambert, Physiological roles of axonal ankyrins in survival of premyelinated axons and localization of voltage-gated sodium channels, Journal of Neurocytology, vol.28, issue.4/5, pp.303-318, 1999.
DOI : 10.1023/A:1007005528505

N. Blom, T. Sicheritz-ponten, R. Gupta, S. Gammeltoft, and S. Brunak, Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence, PROTEOMICS, vol.4, issue.6, pp.1633-1649, 2004.
DOI : 10.1002/pmic.200300771

T. Boiko, M. N. Rasband, S. R. Levinson, J. H. Caldwell, G. Mandel et al., Compact Myelin Dictates the Differential Targeting of Two Sodium Channel Isoforms in the Same Axon, Neuron, vol.30, issue.1, pp.91-104, 2001.
DOI : 10.1016/S0896-6273(01)00265-3

T. Boiko, A. Van-wart, J. H. Caldwell, S. R. Levinson, J. S. Trimmer et al., Functional Specialization of the Axon Initial Segment by Isoform-Specific Sodium Channel Targeting, The Journal of Neuroscience, vol.23, issue.6, pp.2306-2313, 2003.
DOI : 10.1523/JNEUROSCI.23-06-02306.2003

T. Boiko, M. Vakulenko, H. Ewers, C. C. Yap, C. Norden et al., Ankyrin-Dependent and -Independent Mechanisms Orchestrate Axonal Compartmentalization of L1 Family Members Neurofascin and L1/Neuron-Glia Cell Adhesion Molecule, Journal of Neuroscience, vol.27, issue.3, pp.590-603, 2007.
DOI : 10.1523/JNEUROSCI.4302-06.2007

G. Bruckner, S. Szeoke, S. Pavlica, J. Grosche, and J. Kacza, Axon initial segment ensheathed by extracellular matrix in perineuronal nets, Neuroscience, vol.138, issue.2, pp.365-375, 2006.
DOI : 10.1016/j.neuroscience.2005.11.068

B. Catimel, M. Layton, N. Church, J. Ross, M. Condron et al., In situ phosphorylation of immobilized receptors on biosensor surfaces: Application to E-cadherin/??-catenin interactions, Analytical Biochemistry, vol.357, issue.2, pp.277-288, 2006.
DOI : 10.1016/j.ab.2006.07.034

H. J. Chung, Y. N. Jan, and L. Y. , Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains, Proc. Natl. Acad. Sci. USA, pp.8870-8875, 2006.
DOI : 10.1126/science.1086998

J. Q. Davis, S. Lambert, and V. Bennett, Molecular composition of the node of Ranvier: identification of ankyrin- binding cell adhesion molecules neurofascin (mucin+/third FNIII domain- ) and NrCAM at nodal axon segments, The Journal of Cell Biology, vol.135, issue.5, pp.1355-1367, 1996.
DOI : 10.1083/jcb.135.5.1355

J. J. Devaux, K. A. Kleopa, E. C. Cooper, and S. S. Scherer, KCNQ2 Is a Nodal K+ Channel, Journal of Neuroscience, vol.24, issue.5, pp.1236-1244, 2004.
DOI : 10.1523/JNEUROSCI.4512-03.2004

Y. Dzhashiashvili, Y. Zhang, J. Galinska, I. Lam, M. Grumet et al., Nodes of Ranvier and axon initial segments are ankyrin G???dependent domains that assemble by distinct mechanisms, The Journal of Cell Biology, vol.70, issue.5, pp.857-870, 2007.
DOI : 10.1083/jcb.143.5.1295

Y. Eshed, K. Feinberg, S. Poliak, H. Sabanay, O. Sarig-nadir et al., Gliomedin Mediates Schwann Cell-Axon Interaction and the Molecular Assembly of the Nodes of Ranvier, Neuron, vol.47, issue.2, pp.215-229, 2005.
DOI : 10.1016/j.neuron.2005.06.026

Y. Eshed, K. Feinberg, D. J. Carey, and E. Peles, Secreted gliomedin is a perinodal matrix component of peripheral nerves, The Journal of Cell Biology, vol.21, issue.3, pp.551-562, 2007.
DOI : 10.1016/j.febslet.2004.06.059

M. P. Fache, A. Moussif, F. Fernandes, P. Giraud, J. J. Garrido et al., Endocytotic elimination and domain-selective tethering constitute a potential mechanism of protein segregation at the axonal initial segment, The Journal of Cell Biology, vol.23, issue.4, pp.571-578, 2004.
DOI : 10.1083/jcb.143.5.1295

O. Filhol, A. Nueda, V. Martel, D. Gerber-scokaert, M. J. Benitez et al., Live-Cell Fluorescence Imaging Reveals the Dynamics of Protein Kinase CK2 Individual Subunits, Molecular and Cellular Biology, vol.23, issue.3, pp.975-987, 2003.
DOI : 10.1128/MCB.23.3.975-987.2003

O. Filhol, J. L. Martiel, and C. Cochet, Protein kinase CK2: a new view of an old molecular complex, EMBO reports, vol.5, issue.4, pp.351-355, 2004.
DOI : 10.1038/sj.embor.7400115

URL : https://hal.archives-ouvertes.fr/hal-00246566

J. J. Garrido, F. Fernandes, P. Giraud, I. Mouret, E. Pasqualini et al., Identification of an axonal determinant in the C-terminus of the sodium channel Nav1.2, The EMBO Journal, vol.20, issue.21, pp.5950-5961, 2001.
DOI : 10.1093/emboj/20.21.5950

J. J. Garrido, P. Giraud, E. Carlier, F. Fernandes, A. Moussif et al., A Targeting Motif Involved in Sodium Channel Clustering at the Axonal Initial Segment, Science, vol.300, issue.5628, pp.2091-2094, 2003.
DOI : 10.1126/science.1085167

S. Ghosh, F. C. Dorsey, and J. V. Cox, CK2 constitutively associates with and phosphorylates chicken erythroid ankyrin and regulates its ability to bind to spectrin, Journal of Cell Science, vol.115, issue.21, pp.4107-4115, 2002.
DOI : 10.1242/jcs.00102

G. Stuart, N. Spruston, B. Sakmann, and M. Hausser, Action potential initiation and backpropagation in neurons of the mammalian CNS, Trends in Neurosciences, vol.20, issue.3, pp.125-131, 1997.
DOI : 10.1016/S0166-2236(96)10075-8

N. Theis-febvre, V. Martel, B. Laudet, C. Souchier, D. Grunwald et al., Highlighting protein kinase CK2 movement in living cells, Molecular and Cellular Biochemistry, vol.270, issue.1-2, pp.15-22, 2005.
DOI : 10.1007/s11010-005-3115-z

URL : https://hal.archives-ouvertes.fr/inserm-00413185

E. K. Wittmack, A. M. Rush, M. J. Craner, M. Goldfarb, S. G. Waxman et al., Fibroblast Growth Factor Homologous Factor 2B: Association with Nav1.6 and Selective Colocalization at Nodes of Ranvier of Dorsal Root Axons, Journal of Neuroscience, vol.24, issue.30, pp.6765-6775, 2004.
DOI : 10.1523/JNEUROSCI.1628-04.2004

Y. Yang, Y. Ogawa, K. L. Hedstrom, and M. N. Rasband, ??IV spectrin is recruited to axon initial segments and nodes of Ranvier by ankyrinG, The Journal of Cell Biology, vol.267, issue.4, pp.509-519, 2007.
DOI : 10.1083/jcb.143.5.1295

D. Zhou, S. Lambert, P. L. Malen, S. Carpenter, L. M. Boland et al., Is Required for Clustering of Voltage-gated Na Channels at Axon Initial Segments and for Normal Action Potential Firing, The Journal of Cell Biology, vol.12, issue.5, pp.1295-1304, 1998.
DOI : 10.1016/S0896-6273(00)80393-1