Synthesis of 6- or 4-functionalized indoles via a reductive cyclization approach and evaluation as aromatase inhibitors

Marie-Pierre Lézé (1) , Anja Palusczak (2) , Rolf W Hartmann (2) , Marc Le Borgne (1)

1 IICiMed - Cibles et Médicaments des Infections et de l'Immunité
2 Saarland University [Saarbrücken]

Domaines: Chimie thérapeutique; Cancer; Sciences pharmaceutiques; Médicaments

Marie-Pierre Lézé, Anja Palusczak, Rolf W Hartmann, Marc Le Borgne. Synthesis of 6- or 4-functionalized indoles via a reductive cyclization approach and evaluation as aromatase inhibitors. Bioorganic and Medicinal Chemistry Letters, 2008, 18 (16), pp.4713 - 4715. ⟨10.1016/j.bmcl.2008.06.094⟩. ⟨hal-01689195⟩