Differentiation Between Fibroblast and their Extracellular Matrix in an In-Vitro Electrical Impedance Spectroscopy Setup by Using a Custom Electronic Portable System

Edwin de Roux (1) , Mehdi Terosiet (1) , Florian Kolbl (1) , Michel Boissière (2) , Philippe Banet (3) , Johnatan Chrun (3) , Pierre-Henry Aubert (3) , Emmanuel Pauthe (2) , Olivier Romain (1) , Aymeric Histace (1)

1 ASTRE [Cergy-Pontoise]
2 ERRMECe - Equipe de recherche sur les relations matrice extracellulaire-cellules
3 LPPI - Laboratoire de Physico-chimie des Polymères et des Interfaces

This article presents the results from an Electrical Impedance Spectroscopy (EIS) measurements by using a custom wireless and portable electronic system. Our goal is to differentiate between cells and their extracellular matrix in the gathered impedance spectrum. These results are used as a part of a research project that aim to find an appropriate electromarker for the detection of the fibrosis induced by active cardiac implants.

Mots clés: electrochemical impedance spectroscopy; wireless cells sensing; fibrous tissue analysis

Domaines: Traitement du signal et de l'image [eess.SP]; Electronique; Biomatériaux

Edwin de Roux, Mehdi Terosiet, Florian Kolbl, Michel Boissière, Philippe Banet, et al.. Differentiation Between Fibroblast and their Extracellular Matrix in an In-Vitro Electrical Impedance Spectroscopy Setup by Using a Custom Electronic Portable System. FETCH 2018 (Ecole d'hiver Francophone sur les Technologies de Conception des Systèmes embarqués Hétérogènes), Jan 2018, Saint Malo, France. ⟨hal-01688973⟩