Synthesis, radiofluorination and pharmacological evaluation of a fluoromethyl spirocyclic PET tracer for central σ1 receptors and comparison with fluoroalkyl homologs

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https://hal.archives-ouvertes.fr/hal-01677635
Contributor : Aurélie Maisonial-Besset <>
Submitted on : Monday, January 8, 2018 - 3:06:39 PM
Last modification on : Thursday, June 20, 2019 - 9:52:06 AM

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Aurélie Maisonial-Besset, Aurélie Maisonial, Eva Große Maestrup, Christian Wiese, Achim Hiller, et al.. Synthesis, radiofluorination and pharmacological evaluation of a fluoromethyl spirocyclic PET tracer for central σ1 receptors and comparison with fluoroalkyl homologs. Bioorganic and Medicinal Chemistry, Elsevier, 2012, 20 (1), pp.257 - 269. ⟨10.1016/j.bmc.2011.11.002⟩. ⟨hal-01677635⟩

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