Poisoning by Anticoagulant Rodenticides in Humans and Animals: Causes and Consequences

Sébastien Lefebvre (1) , Isabelle Fourel (1) , Stéphane Queffélec (2) , Dominique Vodovar (3, 4) , Bruno Mégarbane (3, 4) , Etienne Benoit (1) , Virginie Siguret (5, 6) , Virginie Lattard (1)

1 RS2GP - Rongeurs Sauvages, Risques Sanitaires et Gestion des Populations - UR 1233
2 CNITV - Centre National d’Informations Toxicologiques Vétérinaires
3 VariaPsy - U1144 - Variabilité de réponse aux Psychotropes
4 Service de réanimation médicale et toxicologique [AP-HP Hôpital Lariboisière]
5 IThEM - U1140 - Innovations thérapeutiques en hémostase
6 Service d'hématologie biologique

Anticoagulant rodenticides (ARs) are a keystone of the management of rodent populations in the world. The widespread use of these molecules raises questions on exposure and intoxication risks, which define the safety of these products. Exposures and intoxica-tions can affect humans, domestic animals and wildlife. Consequences are different for each group, from the simple issue of intoxication in humans to public health concern if farm animals are exposed. After a rapid presentation of the mechanism of action and the use of anticoagulant rodenticides, this chapter assesses the prominence of poisoning by anticoagulant rodenticides in humans, domestic animals and wildlife.

Mots clés: anticoagulant; rodent; poisoning; human

Domaines: Médecine vétérinaire et santé animale; Biochimie [q-bio.BM]; Ecotoxicologie; Toxicologie et chaîne alimentaire

Sébastien Lefebvre, Isabelle Fourel, Stéphane Queffélec, Dominique Vodovar, Bruno Mégarbane, et al.. Poisoning by Anticoagulant Rodenticides in Humans and Animals: Causes and Consequences. Poisoning - From Specific Toxic Agents to Novel Rapid and Simplified Techniques for Analysis, 2017, ⟨10.5772/intechopen.69955⟩. ⟨hal-01668708⟩