Data set for transcriptome analysis of Escherichia coli exposed to nickel

Manon Gault (1) , Agnès Rodrigue (2)

1 MAP - Microbiologie, adaptation et pathogénie
2 MTSB - Trafic et signalisation membranaires chez les bactéries

Ni is recognized as an element that is toxic to humans, acting as an allergen and a carcinogenic agent, and it is also toxic to plants. The toxicity of Ni has been understudied in microorganisms. The data presented here were obtained by submitting the model bacterium Escherichia coli K-12 to nickel stress. To identify expressed genes, RNA-Seq was performed. Bacteria were exposed to 50 mM NiCl 2 during 10 min. Exposure to Ni lead to the deregulation of 57% of the E. coli transcripts. Further analysis using DAVID identified most affected biological pathways. The list of differentially expressed genes and physiological consequences of Ni stress are described in " Ni exposure impacts the pool of free Fe and modifies DNA supercoiling via metal-induced oxidative stress in Escherichia coli K-12 "

Mots clés: RNA-Seq; Escherichia coli; nickel

Domaines: Bactériologie; Génomique, Transcriptomique et Protéomique [q-bio.GN]; Biochimie [q-bio.BM]; Biologie moléculaire

Manon Gault, Agnès Rodrigue. Data set for transcriptome analysis of Escherichia coli exposed to nickel. Data in Brief, 2016, 9, pp.314 - 317. ⟨10.1016/j.dib.2016.08.069⟩. ⟨hal-01667550⟩