Preliminary study investigating depth sensitivity of spatially resolved bimodal spectroscopy combined to optical clearing agents on a human skin based-hybrid model

Grégoire Khairallah (1, 2) , Marine Amouroux (1) , Prisca Rakotomanga (1) , Charles Soussen (1) , Frédéric Marchal (3, 1) , Alain Delconte (1) , Wei Feng (4) , Dan Zhu (4) , Walter Blondel (1)

1 CRAN - Centre de Recherche en Automatique de Nancy
2 CHR Metz-Thionville - Centre hospitalier régional Metz-Thionville
3 UNICANCER/ICL - Institut de Cancérologie de Lorraine - Alexis Vautrin [Nancy]
4 HUST - Huazhong University of Science and Technology [Wuhan]

This preliminary study investigates depth sensitivity of spatially resolved-spectroscopy on skin subjected to a sucrose based-OCA. Skin transparency, reflected in estimated optical properties, significantly affects diffuse reflectance and fluorescence spectra collected at longest interfiber distances

Domaines: Traitement du signal et de l'image [eess.SP]; Optique / photonique; Cancer

Grégoire Khairallah, Marine Amouroux, Prisca Rakotomanga, Charles Soussen, Frédéric Marchal, et al.. Preliminary study investigating depth sensitivity of spatially resolved bimodal spectroscopy combined to optical clearing agents on a human skin based-hybrid model. Asia Communications and Photonics Conference, ACP 2017, Nov 2017, Guangzhou, China. ⟨hal-01637545⟩