Holder Pasteurization May Alter the Digestion of Human Milk
Résumé
This month's issue features a report on the 14th annual IMGC Symposium, how cow’s milk may improve cognition, the effects of Holder pasteurization on the milk digestion, and how an infant’s diet influences the development of their immune system
• One way to monitor how a type of food is digested is to mimic the physiological process in the lab.
• Researchers have monitored raw and Holder pasteurized human milk for when the digestion process imitates that of a term-born infant as well as a premature infant.
• Although Holder pasteurization alters milk’s digestive progress in the lab, results form a small clinical trial suggest these differences are slight—if they exist at all—in hospitalized infants.
• More clinical research in this area is required before conclusions can be drawn.
There is a laboratory in Rennes, the capital of Brittany, France that seeks to mimic the interior of the human gut. It has a machine with a compartment that pretends to be a stomach, full of acid and enzymes. Another compartment replicates the conditions of the small intestine. A computer modulates how food, in its various stages of digestion, flows through this system, by altering the activity of peristaltic pumps. In the past couple of years, scientists operating this system have put it to work digesting human milk. And because every aspect of digestion can be finely tuned, they can speed up gastric emptying, lower certain enzymatic activities, and
raise gastric pH—as per a preterm (relative to a term-born) infant’s system. The main question these scientists seek to answer is how pasteurizing milk by heating to 62.5 °C for 30 minutes alters how well it is digested.
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