Acta Cryst, pp.213-221, 2010. ,
Diflunisal Analogues Stabilize the Native State of Transthyretin. Potent Inhibition of Amyloidogenesis, Journal of Medicinal Chemistry, vol.47, issue.2, pp.355-374, 2004. ,
DOI : 10.1021/jm030347n
software suite, Journal of Applied Crystallography, vol.32, issue.3, pp.554-562, 1999. ,
DOI : 10.1107/S0021889898015350
Acta Cryst, pp.271-281, 2011. ,
Synchrotron X-ray studies suggest that the core of the transthyretin amyloid fibril is a continuous ??-sheet helix, Structure, vol.4, issue.8, pp.989-998, 1996. ,
DOI : 10.1016/S0969-2126(96)00104-9
Neutron macromolecular crystallography, Crystallography Reviews, vol.64, issue.1, pp.157-218, 2009. ,
DOI : 10.1107/S0108767307043498
, an X-windows-based program for the processing of Laue diffraction data, Journal of Applied Crystallography, vol.28, issue.2, pp.228-236, 1995. ,
DOI : 10.1107/S002188989400991X
LAUEGEN version 6.0 and INTLDM, Journal of Applied Crystallography, vol.31, issue.3, pp.496-502, 1998. ,
DOI : 10.1107/S0021889897016683
URL : http://journals.iucr.org/j/issues/1998/03/00/hi0058/hi0058.pdf
Neutron cryo-crystallography captures the protonation state of ferryl heme in a peroxidase, Science, vol.60, issue.Pt 12 Pt 1, pp.193-197, 2014. ,
DOI : 10.1107/S0907444904019158
Diflunisal for ATTR Cardiac Amyloidosis, Congestive Heart Failure, vol.18, issue.suppl 1, pp.315-319, 2012. ,
DOI : 10.1016/j.ahj.2012.04.015
A Substructure Combination Strategy To Create Potent and Selective Transthyretin Kinetic Stabilizers That Prevent Amyloidogenesis and Cytotoxicity, Journal of the American Chemical Society, vol.132, issue.4, pp.1359-1370, 2010. ,
DOI : 10.1021/ja908562q
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818972
Structure-based design of kinetic stabilizers that ameliorate the transthyretin amyloidoses, Current Opinion in Structural Biology, vol.20, issue.1, pp.54-62, 2010. ,
DOI : 10.1016/j.sbi.2009.12.009
Tabulation of human transthyretin (TTR) variants, 2003, Amyloid, vol.74, issue.3, pp.160-184, 2003. ,
DOI : 10.1021/ac010780+
Rubredoxin: Implication of Hydronium Ions and Protonation State Equilibria in Redox Changes, Angewandte Chemie International Edition, vol.68, issue.3, pp.1022-1025, 2013. ,
DOI : 10.1107/S0907444911048402
Solution conformations of early intermediates in Mos1 transposition, Nucleic Acids Research, vol.41, issue.3, pp.2020-2033, 2013. ,
DOI : 10.1093/nar/gks1295
MolProbity: all-atom contacts and structure validation for proteins and nucleic acids, Nucleic Acids Research, vol.35, issue.Web Server, pp.375-383, 2007. ,
DOI : 10.1093/nar/gkm216
URL : https://academic.oup.com/nar/article-pdf/35/suppl_2/W375/9583893/gkm216.pdf
The ??-Slip, Molecular Cell, vol.6, issue.5, pp.1207-1218, 2000. ,
DOI : 10.1016/S1097-2765(00)00117-9
Acta Cryst, pp.72-82, 2006. ,
Negative cooperativity in the binding of thyroxine to human serum prealbumin, Biochemistry, vol.14, issue.2, pp.282-289, 1975. ,
DOI : 10.1021/bi00673a014
The ID23-2 structural biology microfocus beamline at the ESRF, Journal of Synchrotron Radiation, vol.5, issue.1, pp.107-118, 2010. ,
DOI : 10.1107/S0909049509041168
URL : http://doi.org/10.1107/s0909049509041168
Neutron fibre diffraction study of DNA hydration, International Journal of Biological Macromolecules, vol.11, issue.4, pp.236-240, 1989. ,
DOI : 10.1016/0141-8130(89)90075-5
-phenylene terephthalamide) from Neutron Fiber Diffraction Studies, Macromolecules, vol.37, issue.25, pp.9654-9656, 2004. ,
DOI : 10.1021/ma048445l
URL : https://hal.archives-ouvertes.fr/hal-00304477
Bilayer-Mediated Clustering and Functional Interaction of MscL Channels, Biophysical Journal, vol.100, issue.5, pp.1252-1260, 2011. ,
DOI : 10.1016/j.bpj.2011.01.023
Binding site asymmetry in human transthyretin 437 ,
Synthesis and Characterization of Potent Bivalent Amyloidosis Inhibitors That Bind Prior to Transthyretin Tetramerization, Journal of the American Chemical Society, vol.125, issue.44, pp.13404-13414, 2003. ,
DOI : 10.1021/ja030294z
Transthyretin: a review from a structural perspective, Cellular and Molecular Life Sciences, vol.58, issue.10, pp.1491-1521, 2001. ,
DOI : 10.1007/PL00000791
Acta Cryst, pp.1428-1431, 2011. ,
Acta Cryst, pp.1413-1417, 2005. ,
The recording and analysis of synchrotron X-radiation Laue diffraction photographs, Journal of Applied Crystallography, vol.22, issue.5, pp.483-497, 1989. ,
DOI : 10.1107/S0021889889006564
A comparative analysis of 23 structures of the amyloidogenic protein transthyretin, Journal of Molecular Biology, vol.302, issue.3, pp.649-669, 2000. ,
DOI : 10.1006/jmbi.2000.4078
Neutron structure of type-III antifreeze protein allows the reconstruction of AFP-ice interface, Journal of Molecular Recognition, vol.74, issue.20, pp.724-732, 2011. ,
DOI : 10.1016/S0006-3495(98)77923-8
URL : https://hal.archives-ouvertes.fr/hal-00629934
Variation in amount of wild-type transthyretin in different fibril and tissue types in ATTR amyloidosis, Journal of Molecular Medicine, vol.355, issue.2, pp.171-180, 2011. ,
DOI : 10.1016/j.jmb.2005.09.100
Amyloid fibril composition is related to the phenotype of hereditary transthyretin V30M amyloidosis, The Journal of Pathology, vol.78, issue.2, pp.253-261, 2008. ,
DOI : 10.1161/01.CIR.58.6.1072
Metal Ion Roles and the Movement of Hydrogen during Reaction Catalyzed by D-Xylose Isomerase: A Joint X-Ray and Neutron Diffraction Study, Structure, vol.18, issue.6, pp.688-699, 2010. ,
DOI : 10.1016/j.str.2010.03.011
Identification of the Elusive Hydronium Ion Exchanging Roles with a Proton in an Enzyme at Lower pH???Values, Angewandte Chemie International Edition, vol.22, issue.33, pp.7520-7523, 2011. ,
DOI : 10.1107/S0021889889006564
A High Angle Neutron Fibre Diffraction Study of the Hydration of the A Conformation of the DNA Double Helix, Journal of Biomolecular Structure and Dynamics, vol.43, issue.3, pp.489-503, 1992. ,
DOI : 10.1002/prot.340120303
L-Arabinose Binding, Isomerization, and Epimerization by D-Xylose Isomerase: X-Ray/Neutron Crystallographic and Molecular Simulation Study, Structure, vol.22, issue.9, pp.1287-1300, 2014. ,
DOI : 10.1016/j.str.2014.07.002
URL : http://doi.org/10.1016/j.str.2014.07.002
Acta Cryst, pp.48-57, 2006. ,
Nearly 200 X-Ray Crystal Structures of Transthyretin: What Do They Tell Us About This Protein and the Design of Drugs for TTR Amyloidoses?, Current Medicinal Chemistry, vol.19, issue.15, pp.2324-2342, 2012. ,
DOI : 10.2174/092986712800269335
A molecular correlate of clinicopathology in transthyretin amyloidosis, The Journal of Pathology, vol.216, issue.1, pp.1-3, 2009. ,
DOI : 10.1177/10.3.355
Familial amyloid polyneuropathy, The Lancet Neurology, vol.10, issue.12, pp.1086-1097, 2011. ,
DOI : 10.1016/S1474-4422(11)70246-0
Evolutionary changes to transthyretin: structure-function relationships, FEBS Journal, vol.132, issue.Suppl 2, pp.5330-5341, 2009. ,
DOI : 10.1210/en.132.5.2254
URL : http://onlinelibrary.wiley.com/doi/10.1111/j.1742-4658.2009.07243.x/pdf
Transthyretin slowly exchanges subunits under physiological conditions: A convenient chromatographic method to study subunit exchange in oligomeric proteins, Protein Science, vol.5, issue.8, pp.1606-1613, 2001. ,
DOI : 10.1110/ps.8901
Hormone delivery systems to the brain - transthyretin, Experimental and Clinical Endocrinology & Diabetes, vol.103, issue.02, pp.75-80, 1995. ,
DOI : 10.1055/s-0029-1211332
Pathogenesis of and Therapeutic Strategies to Ameliorate the Transthyretin Amyloidoses, Current Pharmaceutical Design, vol.14, issue.30, pp.3219-3230, 2008. ,
DOI : 10.2174/138161208786404155
The ???edge strand??? hypothesis: Prediction and test of a mutational ???hot-spot??? on the transthyretin molecule associated with FAP amyloidogenesis, Amyloid, vol.24, issue.2, pp.75-85, 1996. ,
DOI : 10.1107/S0021889891004399
A high-angle neutron fibre diffraction study of the hydration of deuterated A-DNA, Biophysical Chemistry, vol.69, issue.1, pp.85-96, 1997. ,
DOI : 10.1016/S0301-4622(97)00090-2
Neutron Diffraction Studies of a Class A ??-Lactamase Toho-1 E166A/R274N/R276N Triple Mutant, Journal of Molecular Biology, vol.396, issue.4, pp.1070-1080, 2010. ,
DOI : 10.1016/j.jmb.2009.12.036
The active site protonation states of perdeuterated Toho-1 ??-lactamase determined by neutron diffraction support a role for Glu166 as the general base in acylation, FEBS Letters, vol.127, issue.2, pp.364-368, 2011. ,
DOI : 10.1021/ja044210d
Wild-type transthyretin significantly contributes to the formation of amyloid fibrils in familial amyloid polyneuropathy patients with amyloidogenic transthyretin Val30Met, Human Pathology, vol.42, issue.2, pp.236-243, 2011. ,
DOI : 10.1016/j.humpath.2010.06.014
Joint X-ray/Neutron Crystallographic Study of HIV-1 Protease with Clinical Inhibitor Amprenavir: Insights for Drug Design, Journal of Medicinal Chemistry, vol.56, issue.13, pp.5631-5635, 2013. ,
DOI : 10.1021/jm400684f
Integration of single-crystal reflections using area multidetectors, Journal of Applied Crystallography, vol.21, issue.5, pp.471-478, 1988. ,
DOI : 10.1107/S0021889888005400
Acta Cryst, pp.235-242, 2011. ,
Kinetic Stabilization of an Oligomeric Protein by a Single Ligand Binding Event, Journal of the American Chemical Society, vol.127, issue.15, pp.5540-5551, 2005. ,
DOI : 10.1021/ja042929f
Hydrogen-bond network and pH sensitivity in transthyretin: Neutron crystal structure of human transthyretin, Journal of Structural Biology, vol.177, issue.2, pp.283-290, 2012. ,
DOI : 10.1016/j.jsb.2011.12.022