From molecules to living organisms: an Interplay between biology and physics

Abstract : The book gathers lecture notes of courses given at the 2014 summer school on integrated biology in Les Houches, France, Session CII. It addresses an emerging field ranging from molecules to cells and to organisms. Through examples it presents a new way of thinking using a combination of interdisciplinary and cutting-edge methods, bridging physics and biology beyond current biophysics. Important novel developments are expected in the coming years that may well introduce paradigm shifts in biological science. The school had the ambition to prepare participants to become major actors in these breakthroughs. The power of integrated approaches is illustrated through two cases: interactions between viruses and host cells, and flower development. The role of forces in biology, as well as their mathematical modeling, is illustrated in both processes: how they allow flower organs to emerge or how they control membrane fusion during virus budding. The book also underlines the importance of conformational changes and dynamics of proteins particularly during membrane processes. It explains how membrane proteins can be handled and studied by molecular simulations. Finally, the book also contains concepts in cell biology, in thermodynamics and several novel approaches such as in-cell NMR. Altogether, the chapters show how examining a biological system from different viewpoints based on multidisciplinary aspects often leads to enriching controversial arguments.
Type de document :
Direction d'ouvrage, Proceedings, Dossier
Les Houches Summer School, Jul 2014, Les Houches, France. 102 (1ère ed.), Oxford University Press, 464 p., 2016, 978-0-19-875295-0
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https://hal.archives-ouvertes.fr/hal-01607715
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Soumis le : mardi 3 octobre 2017 - 00:12:21
Dernière modification le : lundi 27 novembre 2017 - 10:58:02

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  • HAL Id : hal-01607715, version 1
  • PRODINRA : 393367

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INRA | CEA | UPMC | LPTHE

Citation

Eva Pebay Peyroula, Hugues Nury, François Parcy, Rob W. H. Ruigrok, Christine Ziegler, et al.. From molecules to living organisms: an Interplay between biology and physics. Les Houches Summer School, Jul 2014, Les Houches, France. 102 (1ère ed.), Oxford University Press, 464 p., 2016, 978-0-19-875295-0. 〈hal-01607715〉

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