THE ROLE OF CORTICAL BONE MICROSTRUCTURE IN THE EFFECTIVE MESOSCOPIC ELASTIC PROPERTIES

Xiran Cai (1) , Renald Brenner (2) , Laura Peralta (1) , Cécile Olivier (3, 4) , Pierre-Jean Gouttenoire (3, 4) , Françoise Peyrin (4, 5) , Pascal Laugier (1) , Quentin Grimal (1)

1 LIB - Laboratoire d'Imagerie Biomédicale [Paris]
2 DALEMBERT - Institut Jean Le Rond d'Alembert
3 Imagerie Tomographique et Radiothérapie
4 ESRF - European Synchrotron Radiation Facility
5 CREATIS - Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé

The vascular porosity of cortical bone is a major determinant of the variation in mesoscopic (millimeterscale) stiffness [1]. However, porosity was regarded as a fraction of void volume in the study. To better understand bone mechanical behavior, the role of pore network microarchitecture should not be ignored. This work aims to investigate the relationship between microstructure and mesoscopic stiffness of human cortical bone. The microstructure and anisotropic stiffness were experimentally quantified. Also, in order to control for the effect of inter-specimen bone mineralized matrix elasticity variations, the stiffness was obtained by homogenization.

Domaines: Sciences du Vivant [q-bio]; Imagerie

Xiran Cai, Renald Brenner, Laura Peralta, Cécile Olivier, Pierre-Jean Gouttenoire, et al.. THE ROLE OF CORTICAL BONE MICROSTRUCTURE IN THE EFFECTIVE MESOSCOPIC ELASTIC PROPERTIES. 23rd Congress of the European Society of Biomechanics, Jul 2017, Seville, Spain. ⟨hal-01598216⟩