Assessment of imaging quality in magnified phase CT of human bone tissue at the nanoscale
Résumé
We use magnified X-ray phase nano-CT to quantify bone ultra-structure in human femoral bone, by using the new ID16A beamline at the ESRF to reach a voxel size of 10nm. Since image quality is essential for the quantification of bone tissue, our aim is to evaluate different phase retrieval methods for this application. Our results, based on visual and quantitative assessment, show that the use of several distances (as opposed to one) decisively improves image quality (at 120 and 30 nm) and that the two considered multi-distance phase retrieval methods (based on Paganin and CTF approaches) give similar results.