Single histidine residue in head-group region is sufficient to impart remarkable gene transfection properties to cationic lipids: evidence for histidine-mediated membrane fusion at acidic pH

V Kumar (1) , Chantal Pichon (2) , M. Refregiers (2) , B Guerin (2) , P. Midoux (2) , A. Chaudhuri (1)

1 IICT - CSIR Indian Institute of Chemical Technology
2 CBM - Centre de biophysique moléculaire

Domaines: Biophysique

V Kumar, Chantal Pichon, M. Refregiers, B Guerin, P. Midoux, et al.. Single histidine residue in head-group region is sufficient to impart remarkable gene transfection properties to cationic lipids: evidence for histidine-mediated membrane fusion at acidic pH. Gene Therapy, 2002, 10 (15), pp.1206 - 1215. ⟨10.1038/sj.gt.3301979⟩. ⟨hal-01596052⟩