Wet granulation: the effect of shear on granule properties

Driss Oulahna (1) , F Cordier (1) , Laurence Galet (1) , John A. Dodds (1)

1 Poudres et procédés - Ecole des Mines Albi-Carmaux

This paper presents a study of the wet granulation of fine cosmetic particles using a high-shear mixer granulator on a given particle and binder system. The shear effect on granule properties is highlighted. The granules formed under different impeller speeds are divided into size classes and further examined in terms of porosity, friability and binder content. The main result of this study is that, depending on operating conditions, the granulation of a fine powder with a given binding liquid can result in the formation of granules of very different characteristics in terms of size, porosity and friability. Mechanical energy brought to the granulation system is as important as the physicochemical characteristics of the powder-binder pair.

Mots clés: Binder content; Friability; friability; binder content; porosity; high-shear mixer; Wet granulation; High-shear mixer; Porosity

Domaines: Génie des procédés; Génie chimique

Driss Oulahna, F Cordier, Laurence Galet, John A. Dodds. Wet granulation: the effect of shear on granule properties. Powder Technology, 2003, 130 (1-3), pp.238-246. ⟨10.1016/S0032-5910(02)00272-3⟩. ⟨hal-01593344⟩