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Article Dans Une Revue RSC Advances Année : 2017

Synthesis and anticancer activity of prodigiosenes bearing C-ring esters and amides

Résumé

Prodigiosenes, a class of compounds characterised by their 4-methoxypyrrolyldipyrrin framework, are known to possess anti-cancer activity. Structural modification of the C-ring of prodigiosenes presented ten new prodigiosenes bearing pendant alkyl esters and amides. These prodigiosenes were evaluated biologically and displayed notable anticancer in vitro activity, particularly when featuring a hexyl chain.
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hal-01588468 , version 1 (15-09-2017)

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Kate-Lyn A. R. Lund, Carlotta Figliola, Aleksandra K. Kajetanowicz, Alison Thompson. Synthesis and anticancer activity of prodigiosenes bearing C-ring esters and amides. RSC Advances, 2017, 7 (30), pp.18617-8627. ⟨10.1039/c7ra01628j⟩. ⟨hal-01588468⟩
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