Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe

Elodie A. Pérès (1, 2) , An Gérault (2, 1) , S Valable (2, 1) , S Roussel (2, 1) , J Toutain (2, 1) , D Divoux (2, 1) , Js Guillamo (2, 1, 3) , M Sanson (4) , M Bernaudin (2, 1) , E Petit (2, 1)

1 ISTCT - Imagerie et Stratégies Thérapeutiques des pathologies Cérébrales et Tumorales
2 CERVOxy - Hypoxie, physiopathologies cérébrovasculaire et tumorale
3 Service de Neurologie [CHU Caen]
4 ICM - Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute

Mots clés: senescence; ionising radiation; erythropoietin receptor; temozolomide; brain tumour; mitotic death

Domaines: Sciences du Vivant [q-bio]

Elodie A. Pérès, An Gérault, S Valable, S Roussel, J Toutain, et al.. Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe. Oncotarget, 2015, 6 (4), pp.2101-19. ⟨10.18632/oncotarget.2937⟩. ⟨hal-01576268⟩