Multimodal imaging based on MRI and PET reveals [(18)F]FLT PET as a specific and early indicator of treatment efficacy in a preclinical model of recurrent glioblastoma

A Corroyer-Dulmont (1) , Elodie A. Pérès (1) , An Gérault (1) , A Savina (2) , F Bouquet (2) , D Divoux (1) , J Toutain (1) , M Ibazizène (1) , Et Mackenzie (1) , L Barré (1) , M Bernaudin (1) , E Petit (1) , S Valable (1)

1 ISTCT - Imagerie et Stratégies Thérapeutiques des pathologies Cérébrales et Tumorales
2 Roche SAS, 30, cours de l'Ile Seguin, 92650, Boulogne-Billancourt, France.

Mots clés: MRI; PET; Recurrence; Treatment efficacy; Glioblastoma; Imaging biomarker

Domaines: Sciences du Vivant [q-bio]

A Corroyer-Dulmont, Elodie A. Pérès, An Gérault, A Savina, F Bouquet, et al.. Multimodal imaging based on MRI and PET reveals [(18)F]FLT PET as a specific and early indicator of treatment efficacy in a preclinical model of recurrent glioblastoma. European Journal of Nuclear Medicine and Molecular Imaging, 2016, 43 (4), pp.682-694. ⟨10.1007/s00259-015-3225-0⟩. ⟨hal-01575614⟩