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Nuclear incorporation of iron during the eukaryotic cell cycle

Abstract : Scanning X-ray fluorescence microscopy has been used to probe the distribution of S, P and Fe within cell nuclei. Nuclei, which may have originated at different phases of the cell cycle, are found to show very different levels of Fe present with a strongly inhomogeneous distribution. P and S signals, presumably from DNA and associated nucleosomes, are high and relatively uniform across all the nuclei; these agree with X-ray phase contrast projection microscopy images of the same samples. Possible reasons for the Fe incorporation are discussed
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Ian Robinson, Yang Yang, Fucai Zhang, Christophe Lynch, Mohammed Yusuf, et al.. Nuclear incorporation of iron during the eukaryotic cell cycle. Journal of Synchrotron Radiation, International Union of Crystallography, 2016, 23, pp.1490-1497. ⟨10.1107/S1600577516012807⟩. ⟨hal-01572923⟩



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