Homozygous transcription factor 3 gene (TCF3) mutation is associated with severe hypogammaglobulinemia and B-cell acute lymphoblastic leukemia.

Meriem Ben-Ali (1, 2) , Jing Yang (3) , Koon Wing Chan (3) , Imen Ben-Mustapha (1, 2) , Najla Mekki (2, 1) , Chaouki Benabdesselem (1, 2) , Fethi Mellouli (4) , Mohamed Bejaoui (4) , Wanling Yang (3) , Lamia Aissaoui (2, 5) , Yu Lung Lau (3) , Mohamed-Ridha Barbouche (1, 2)

1 LR11IPT02 - Laboratoire de Transmission, Contrôle et Immunobiologie des Infections - Laboratory of Transmission, Control and Immunobiology of Infection
2 UTM - Université de Tunis El Manar
3 Department of Paediatrics and Adolescent Medicine [HKU]
4 CNGMO - Centre National de Greffe de la Moëlle osseuse Tunis
5 Aziza Othmana Hospital [Tunis]

Letter to the Editor

Domaines: Immunologie; Médecine humaine et pathologie; Génomique, Transcriptomique et Protéomique [q-bio.GN]

Meriem Ben-Ali, Jing Yang, Koon Wing Chan, Imen Ben-Mustapha, Najla Mekki, et al.. Homozygous transcription factor 3 gene (TCF3) mutation is associated with severe hypogammaglobulinemia and B-cell acute lymphoblastic leukemia.. Journal of Allergy and Clinical Immunology, 2017, 140 (4), pp.1191-1194.e4. ⟨10.1016/j.jaci.2017.04.037⟩. ⟨hal-01571310⟩