Environmental seasonality drives digital populations towards stable cross-feeding

Abstract : Stable bacterial cross-feeding interactions, where one strain feeds on the waste of the other, are important to understand, as they can be a first step towards bacterial speciation. Their emergence is commonly observed in laboratory experiments using Escherichia coli as a model organism. Yet it is not clear how cross-feeding interactions can resist the invasion of a fitter mutant when the environment contains a single resource since there seems to be a single ecological niche. Here, we used digital organisms to tackle this question, allowing for detailed and fast investigations, and providing a way to disentangle generic evolutionary mechanisms from speci-ficities associated with E. coli. Digital organisms with evolv-able genomes and metabolic networks compete for resources in conditions mimicking laboratory evolution experiments. In chemostat simulations, although cross-feeding interactions regularly emerged, selective sweeps regularly purged the population of its diversity. By contrast, batch culture allowed for much more stable cross-feeding interactions, because it includes seasons and thus distinct temporal niches, thereby favoring the adaptive diversification of proto-species.
Document type :
Conference papers
Complete list of metadatas

Cited literature [5 references]  Display  Hide  Download

https://hal.archives-ouvertes.fr/hal-01569093
Contributor : Guillaume Beslon <>
Submitted on : Wednesday, July 26, 2017 - 11:55:53 AM
Last modification on : Monday, February 10, 2020 - 4:36:52 PM

File

ECAL_2017_paper_81.pdf
Files produced by the author(s)

Identifiers

  • HAL Id : hal-01569093, version 1

Citation

Charles Rocabert, Carole Knibbe, Jessika Consuegra, Dominique Schneider, Guillaume Beslon. Environmental seasonality drives digital populations towards stable cross-feeding. European Conference on Artificial Life (ECAL), Sep 2017, Villeurbanne, France. ⟨hal-01569093⟩

Share

Metrics

Record views

665

Files downloads

240