Wide-field optical coherence tomography: imaging of biological tissues

E. Bordenave (1) , Emmanuel Abraham (1) , Gediminas Jonusauskas (1) , N. Tsurumachi (1) , J. Oberle (1) , C. Rulliere (1) , P. E. Minot (2) , M. Lassegues (2) , J. E. S. Bazeille (2)

1 CPMOH - Centre de physique moléculaire optique et hertzienne
2 FDRC - Facteurs de Défense et de Régulation Cellulaire

We describe a two-dimensional optical coherence tomography technique with which we were able to obtain multiple longitudinal slices of a biological sample directly in a single Z scan. The system is based on a femtosecond Cr4+:forsterite laser and an infrared camera for wide-field imaging of the sample with a depth resolution of 5 µm. With this imaging apparatus we were able to investigate human skin and mouse ear samples and to observe the different constitutive tissues.

Domaines: Physique [physics]; Optique [physics.optics]

E. Bordenave, Emmanuel Abraham, Gediminas Jonusauskas, N. Tsurumachi, J. Oberle, et al.. Wide-field optical coherence tomography: imaging of biological tissues. Applied optics, 2002, 41 (10), pp.2059-2064. ⟨hal-01550807⟩