Solvent suppression in DNP enhanced solid state NMR

Jayasubba Reddy Yarava (1) , Sachin Rama Chaudhari (1) , Aaron J. Rossini (1, 2) , Anne Lesage (3) , Lyndon Emsley (1)

1 EPFL - Ecole Polytechnique Fédérale de Lausanne
2 Department of Chemistry [Ames]
3 Solid-State NMR Methods for Materials - Méthodes de RMN à l'état solide pour les matériaux

We show how DNP enhanced solid-state NMR spectra can be dramatically simplified by suppression of solvent signals. This is achieved by (i) exploiting the paramagnetic relaxation enhancement of solvent signals relative to materials substrates, or (ii) by using short cross-polarization contact times to transfer hyperpolarization to only directly bonded carbon-13 nuclei in frozen solutions. The methods are evaluated for organic microcrystals, surfaces and frozen solutions. We show how this allows for the acquisition of high-resolution DNP enhanced proton-proton correlation experiments to measure inter-nuclear proximities in an organic solid

Mots clés: Solid-state NMR; DNP; Solvent suppression; Paramagnetic relaxation enhancement (PRE); Relaxation filters

Domaines: Chimie analytique

Jayasubba Reddy Yarava, Sachin Rama Chaudhari, Aaron J. Rossini, Anne Lesage, Lyndon Emsley. Solvent suppression in DNP enhanced solid state NMR. Journal of Magnetic Resonance, 2017, 277, pp.149-153. ⟨10.1016/j.jmr.2017.02.016⟩. ⟨hal-01540073⟩