J. D. Currey, Bones: structure and mechanics, 2002.
DOI : 10.1515/9781400849505

S. Weiner and H. Wagner, THE MATERIAL BONE: Structure-Mechanical Function Relations, Annual Review of Materials Science, vol.28, issue.1, pp.271-298, 1998.
DOI : 10.1146/annurev.matsci.28.1.271

J. Currey, MATERIALS SCIENCE: Hierarchies in Biomineral Structures, Science, vol.309, issue.5732, pp.253-254, 2005.
DOI : 10.1126/science.1113954

P. Fratzl, Biomimetic materials research: what can we really learn from nature's structural materials?, Journal of The Royal Society Interface, vol.4, issue.15, pp.637-642, 2007.
DOI : 10.1098/rsif.2007.0218
URL : http://rsif.royalsocietypublishing.org/content/royinterface/4/15/637.full.pdf

W. Wagermaier, K. Klaushofer, and P. Fratzl, Fragility of Bone Material Controlled by Internal Interfaces, Calcified Tissue International, vol.89, issue.e139, pp.201-212, 2015.
DOI : 10.1210/jc.2003-031055

L. Bonewald, The amazing osteocyte, Journal of Bone and Mineral Research, vol.58, issue.(suppl1), pp.229-238, 2011.
DOI : 10.1093/jmicro/dfp032
URL : http://onlinelibrary.wiley.com/doi/10.1002/jbmr.320/pdf

F. S. Utku, E. Klein, H. Saybasili, C. A. Yucesoy, and S. Weiner, Probing the role of water in lamellar bone by dehydration in the environmental scanning electron microscope, Journal of Structural Biology, vol.162, issue.3, pp.361-367, 2008.
DOI : 10.1016/j.jsb.2008.01.004

A. M. Parfitt, Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee, Journal of Bone and Mineral Research, vol.10, issue.6, pp.595-610, 1987.
DOI : 10.7326/0003-4819-106-1-114

J. G. Skedros, J. L. Holmes, E. G. Vajda, and R. D. Bloebaum, Cement lines of secondary osteons in human bone are not mineraldeficient: New data in a historical perspective, Anat. Rec, vol.286, pp.781-803, 2005.

M. M. Giraud-guille, G. Mosser, C. Helary, and D. Eglin, Bone matrix like assemblies of collagen: From liquid crystals to gels and biomimetic materials, Micron, vol.36, issue.7-8, pp.602-608, 2005.
DOI : 10.1016/j.micron.2005.07.005

W. Wagermaier, Spiral twisting of fiber orientation inside bone lamellae, Biointerphases, vol.1, issue.1, 2006.
DOI : 10.1116/1.2178386

S. Weiner and W. Traub, Bone structure: from angstroms to microns, FASEB J, vol.6, pp.879-885, 1992.

P. Fratzl, H. Gupta, E. Paschalis, and P. Roschger, Structure and mechanical quality of the collagen???mineral nano-composite in bone, J. Mater. Chem., vol.450, issue.14, pp.2115-2123, 2004.
DOI : 10.1098/rspa.1995.0075

P. Schneider, M. Meier, R. Wepf, and R. Müller, Towards quantitative 3D imaging of the osteocyte lacuno-canalicular network, Bone, vol.47, issue.5, pp.848-858, 2010.
DOI : 10.1016/j.bone.2010.07.026

Y. Barad, H. Eisenberg, M. Horowitz, and Y. Silberberg, Nonlinear scanning laser microscopy by third harmonic generation, Applied Physics Letters, vol.93, issue.8, pp.922-924, 1997.
DOI : 10.1364/OL.21.000988

M. Müller, J. Squier, K. Wilson, and G. Brackenhoff, 3D microscopy of transparent objects using third-harmonic generation, Journal of Microscopy, vol.191, issue.3, pp.266-274, 1998.
DOI : 10.1046/j.1365-2818.1998.00399.x

D. Débarre, Imaging lipid bodies in cells and tissues using third-harmonic generation microscopy, Nature Methods, vol.61, issue.1, pp.47-53, 2006.
DOI : 10.1038/nmeth813

F. Aptel, Multimodal Nonlinear Imaging of the Human Cornea, Investigative Opthalmology & Visual Science, vol.51, issue.5, pp.2459-65, 2010.
DOI : 10.1167/iovs.09-4586
URL : https://hal.archives-ouvertes.fr/hal-00526653

M. Rehberg, F. Krombach, U. Pohl, and S. Dietzel, Label-Free 3D Visualization of Cellular and Tissue Structures in Intact Muscle with Second and Third Harmonic Generation Microscopy, PLoS ONE, vol.63, issue.11, p.28237, 2011.
DOI : 10.1371/journal.pone.0028237.s003

B. Weigelin, G. Bakker, and P. Friedl, Intravital third harmonic generation microscopy of collective melanoma cell invasion, IntraVital, vol.310, issue.1, pp.32-43, 2012.
DOI : 10.1021/bi900870u

C. Sun, Higher harmonic generation microscopy for developmental biology, Journal of Structural Biology, vol.147, issue.1, pp.19-30, 2004.
DOI : 10.1016/j.jsb.2003.10.017

S. Witte, Label-free live brain imaging and targeted patching with third-harmonic generation microscopy, Proc. Natl. Acad. Sci. USA, pp.5970-5975, 2011.
DOI : 10.1016/j.mcn.2009.07.013
URL : http://www.pnas.org/content/108/15/5970.full.pdf

G. J. Tserevelakis, Label-Free Imaging of Lipid Depositions in C. elegans Using Third-Harmonic Generation Microscopy, PLoS ONE, vol.16, issue.1, p.84431, 2014.
DOI : 10.1371/journal.pone.0084431.s001

D. Débarre, N. Olivier, W. Supatto, and E. Beaurepaire, Mitigating Phototoxicity during Multiphoton Microscopy of Live Drosophila Embryos in the 1.0???1.2 ??m Wavelength Range, PLoS ONE, vol.9, issue.8, p.104250, 2014.
DOI : 10.1371/journal.pone.0104250.s004

N. Olivier, Cell Lineage Reconstruction of Early Zebrafish Embryos Using Label-Free Nonlinear Microscopy, Science, vol.136, issue.12, pp.967-71, 2010.
DOI : 10.1242/dev.034421
URL : https://hal.archives-ouvertes.fr/hal-00519834

S. Dietzel, Label-Free Determination of Hemodynamic Parameters in the Microcirculaton with Third Harmonic Generation Microscopy, PLoS ONE, vol.454, issue.6, p.99615, 2014.
DOI : 10.1371/journal.pone.0099615.s003

D. Oron, Depth-resolved structural imaging by third-harmonic generation microscopy, Journal of Structural Biology, vol.147, issue.1, pp.3-11, 2004.
DOI : 10.1016/S1047-8477(03)00125-4

M. Kerschnitzki, The organization of the osteocyte network mirrors the extracellular matrix orientation in bone, Journal of Structural Biology, vol.173, issue.2, pp.303-311, 2011.
DOI : 10.1016/j.jsb.2010.11.014

M. Langer, X-Ray Phase Nanotomography Resolves the 3D Human Bone Ultrastructure, PLoS ONE, vol.7, issue.8, p.35691, 2012.
DOI : 10.1371/journal.pone.0035691.s005
URL : https://hal.archives-ouvertes.fr/hal-00827779

P. Milanovic, Osteocytic Canalicular Networks: Morphological Implications for Altered Mechanosensitivity, ACS Nano, vol.7, issue.9, pp.7542-7551, 2013.
DOI : 10.1021/nn401360u

L. You, S. Weinbaum, S. C. Cowin, and M. B. Schaffler, Ultrastructure of the osteocyte process and its pericellular matrix, The Anatomical Record, vol.22, issue.2, pp.505-513, 2004.
DOI : 10.1002/ar.a.20050

G. Marotti, M. Ferretti, F. Remaggi, and C. Palumbo, Quantitative evaluation on osteocyte canalicular density in human secondary osteons, Bone, vol.16, issue.1, pp.125-128, 1995.
DOI : 10.1016/8756-3282(95)80022-I

G. C. Reilly, H. F. Knapp, A. Stemmer, P. Niederer, and M. L. Knothe-tate, Investigation of the Morphology of the Lacunocanalicular System of Cortical Bone Using Atomic Force Microscopy, Annals of Biomedical Engineering, vol.29, issue.12, pp.1074-81, 2001.
DOI : 10.1114/1.1424910

L. Cardoso, S. P. Fritton, G. Gailani, M. Benalla, and S. C. Cowin, Advances in assessment of bone porosity, permeability and interstitial fluid flow, Journal of Biomechanics, vol.46, issue.2, pp.253-265, 2013.
DOI : 10.1016/j.jbiomech.2012.10.025

A. Pacureanu, M. Langer, E. Boller, P. Tafforeau, and F. Peyrin, Nanoscale imaging of the bone cell network with synchrotron X-ray tomography: optimization of acquisition setup, Medical Physics, vol.42, issue.4, p.2229, 2012.
DOI : 10.1111/j.1474-9726.2010.00633.x
URL : https://hal.archives-ouvertes.fr/hal-00797999

K. M. Reiser, Quantitative analysis of structural disorder in intervertebral disks using second harmonic generation imaging: comparison with morphometric analysis, Journal of Biomedical Optics, vol.12, issue.6, 2007.
DOI : 10.1117/1.2812631

A. E. Tuer, Hierarchical Model of Fibrillar Collagen Organization for Interpreting the Second-Order Susceptibility Tensors in Biological Tissue, Biophysical Journal, vol.103, issue.10, pp.2093-2105, 2012.
DOI : 10.1016/j.bpj.2012.10.019

R. Ambekar, M. Chittenden, I. Jasiuk, and K. C. Toussaint, Quantitative second-harmonic generation microscopy for imaging porcine cortical bone: Comparison to SEM and its potential to investigate age-related changes, Bone, vol.50, issue.3, pp.643-650, 2012.
DOI : 10.1016/j.bone.2011.11.013

T. T. Tang, Shear deformation and fracture of human cortical bone, Bone, vol.71, pp.25-35, 2015.
DOI : 10.1016/j.bone.2014.10.001

M. Houle, Analysis of forward and backward Second Harmonic Generation images to probe the nanoscale structure of collagen within bone and cartilage, Journal of Biophotonics, vol.123, issue.6, pp.993-1001, 2015.
DOI : 10.1364/OE.15.007296

P. Stoller, P. M. Celliers, K. M. Reiser, and A. M. Rubenchik, Quantitative second-harmonic generation microscopy in collagen, Applied Optics, vol.42, issue.25, pp.5209-5219, 2003.
DOI : 10.1364/AO.42.005209

A. Erikson, J. Örtegren, T. Hompland, C. L. Davies, and M. Lindgren, Quantification of the second-order nonlinear susceptibility of collagen I using a laser scanning microscope, Journal of Biomedical Optics, vol.12, issue.4, p.44002, 2007.
DOI : 10.1117/1.2772311

A. Deniset-besseau, D. S. Peixoto, P. Mosser, and G. M. Schanne-klein, Nonlinear optical imaging of lyotropic cholesteric liquid crystals, Optics Express, vol.18, issue.2, pp.1113-1121, 2010.
DOI : 10.1364/OE.18.001113.m001
URL : https://hal.archives-ouvertes.fr/hal-00497888

X. Y. Chen, O. Nadiarynkh, S. Plotnikov, and P. J. Campagnola, Second harmonic generation microscopy for quantitative analysis of collagen fibrillar structure, Nature Protocols, vol.28, issue.4, pp.654-669, 2012.
DOI : 10.1364/OE.18.019339

M. M. Giraud-guille, Twisted plywood architecture of collagen fibrils in human compact bone osteons, Calcified Tissue International, vol.47, issue.3, pp.167-180, 1988.
DOI : 10.1007/978-3-642-82657-3_36

S. Weiner, T. Arad, I. Sabanay, and W. Traub, Rotated plywood structure of primary lamellar bone in the rat: Orientations of the collagen fibril arrays, Bone, vol.20, issue.6, pp.509-514, 1997.
DOI : 10.1016/S8756-3282(97)00053-7

S. Weiner, W. Traub, and H. D. Wagner, Lamellar Bone: Structure???Function Relations, Journal of Structural Biology, vol.126, issue.3, pp.241-255, 1999.
DOI : 10.1006/jsbi.1999.4107

P. Varga, Investigation of the three-dimensional orientation of mineralized collagen fibrils in human lamellar bone using synchrotron X-ray phase nano-tomography, Acta Biomaterialia, vol.9, issue.9, pp.8118-8127, 2013.
DOI : 10.1016/j.actbio.2013.05.015

B. Hesse, Canalicular Network Morphology Is the Major Determinant of the Spatial Distribution of Mass Density in Human Bone Tissue: Evidence by Means of Synchrotron Radiation Phase-Contrast nano-CT, Journal of Bone and Mineral Research, vol.104, issue.40, pp.346-356, 2016.
DOI : 10.1073/pnas.0707246104
URL : https://hal.archives-ouvertes.fr/hal-01123891

P. Dong, 3D osteocyte lacunar morphometric properties and distributions in human femoral cortical bone using synchrotron radiation micro-CT images, Bone, vol.60, pp.172-185, 2014.
DOI : 10.1016/j.bone.2013.12.008
URL : https://hal.archives-ouvertes.fr/hal-00976965

P. Dong, QUANTIFICATION OF THE 3D MORPHOLOGY OF THE BONE CELL NETWORK FROM SYNCHROTRON MICRO-CT IMAGES, Image Analysis & Stereology, vol.33, issue.2, pp.157-166, 2014.
DOI : 10.5566/ias.v33.p157-166
URL : https://hal.archives-ouvertes.fr/hal-01052960

C. Ciani, S. B. Doty, and S. P. Fritton, An effective histological staining process to visualize bone interstitial fluid space using confocal microscopy, Bone, vol.44, issue.5, pp.1015-1017, 2009.
DOI : 10.1016/j.bone.2009.01.376
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825028/pdf

Y. Bala, D. Farlay, P. D. Delmas, P. J. Meunier, and G. Boivin, Time sequence of secondary mineralization and microhardness in cortical and cancellous bone from ewes, Bone, vol.46, issue.4, pp.1204-1212, 2010.
DOI : 10.1016/j.bone.2009.11.032

M. Aido, Relationship between nanoscale mineral properties and calcein labeling in mineralizing bone surfaces, Connective Tissue Research, vol.55, issue.sup1, pp.15-17, 2014.
DOI : 10.1002/jbmr.1818
URL : https://hal.archives-ouvertes.fr/hal-01111212

P. Mahou, Multicolor two-photon tissue imaging by wavelength mixing, Nature Methods, vol.2011, issue.8, pp.815-818, 2012.
DOI : 10.1038/nprot.2009.130
URL : https://hal.archives-ouvertes.fr/hal-00324345

J. Squier, M. Muller, G. Brakenhoff, and K. Wilson, Third harmonic generation microscopy, Optics Express, vol.3, issue.9, pp.315-324, 1998.
DOI : 10.1364/OE.3.000315.m005

J. Cheng and X. Xie, Green's function formulation for third-harmonic generation microscopy, Journal of the Optical Society of America B, vol.19, issue.7, pp.1604-1610, 2002.
DOI : 10.1364/JOSAB.19.001604
URL : http://bernstein.harvard.edu/papers/jixin_josa_2002b.pdf

D. Debarre, W. Supatto, and E. Beaurepaire, Structure sensitivity in third-harmonic generation microscopy, Optics Letters, vol.30, issue.16, pp.2134-2136, 2005.
DOI : 10.1364/OL.30.002134
URL : https://hal.archives-ouvertes.fr/hal-00681937

M. B. Schaffler, D. B. Burr, and R. G. Frederickson, Morphology of the osteonal cement line in human bone, The Anatomical Record, vol.37, issue.3, pp.223-228, 1987.
DOI : 10.1007/978-1-349-01604-4_22

P. Chavassieux, M. Arlot, and P. J. Meunier, Clinical Use of Bone Biopsy, pp.501-509, 2001.
DOI : 10.1016/B978-012470862-4/50064-7

I. Arganda-carreras, Consistent and Elastic Registration of Histological Sections Using Vector-Spline Regularization, Lecture Notes in Computer Science, vol.4241, pp.85-95, 2006.
DOI : 10.1007/11889762_8

A. F. Frangi, W. J. Niessen, K. L. Vinc, and M. A. Viergever, Multiscale vessel enhancement filtering, Lecture Notes in Computer Science, vol.191, issue.6, pp.130-137, 1998.
DOI : 10.1148/radiology.191.1.8134563
URL : http://www.tecn.upf.es/~afrangi/articles/miccai1998.pdf

T. Lee, R. Kashyap, and C. Chu, Building Skeleton Models via 3-D Medial Surface Axis Thinning Algorithms, CVGIP: Graphical Models and Image Processing, vol.56, issue.6, pp.462-478, 1994.
DOI : 10.1006/cgip.1994.1042