Near infrared two photon imaging using a bright cationic Yb(III) bioprobe spontaneously internalized into live cells

Anh Thy Bui (1) , Maryline Beyler (2) , Alexei Grichine (3) , Alain Duperray (3) , Jean-Christophe Mulatier (1) , Yannick Guyot (4, 3) , Chantal Andraud (1) , Raphaël Tripier (2) , Sophie Brasselet (5) , Olivier Maury (1)

1 LC - Laboratoire de Chimie - UMR5182
2 CEMCA - Chimie, Electrochimie Moléculaires et Chimie Analytique
3 ILM - Institut Lumière Matière [Villeurbanne]
4 UGA [2016-2019] - Université Grenoble Alpes [2016-2019]
5 MOSAIC - MOSAIC

An Yb(III) complex based on a dimethyl cyclen macrocyclic ligand functionalized by charge transfer antennae was prepared. This cationic [YbL3]+ complex is stable and soluble in water and presents interesting photophysical nonlinear properties. It is spontaneously internalized and accumulates in live cells. High quality images have been obtained both in a classical NIR-to-vis configuration and in the more challenging NIR-to-NIR one.

Domaines: Catalyse; Matériaux; Chimie organique; Chimie inorganique

Anh Thy Bui, Maryline Beyler, Alexei Grichine, Alain Duperray, Jean-Christophe Mulatier, et al.. Near infrared two photon imaging using a bright cationic Yb(III) bioprobe spontaneously internalized into live cells. Chemical Communications, 2017, 53, pp.6005-6008 ⟨10.1039/C7CC02835K⟩. ⟨hal-01526221⟩