Antioxidant activities of peptoid-grafted chitosan films.

P-H. Elchinger (1, 2) , C. Delattre (2) , S. Faure (1) , O. Roy (1) , S. Badel (3) , T. Bernardi (3) , P. Michaud (2) , C. Taillefumier (1)

1 ICCF - Institut de Chimie de Clermont-Ferrand
2 IP - Institut Pascal
3 BioFilm Control, Biopôle Clermont Limagne, Saint-Beauzire

The aim of this study was to investigate the possibility of immobilizing peptoid on chitosan film in order to generate new active material. Chitosan films have been grafted for the first time with short-length peptoid oligomers displaying antioxidant activities. The antioxidant activity of the selected peptoids was initially investigated with the DPPH assay and hydroxyl radical procedure. The metal chelating capacity of peptoids was also evaluated prior to their covalent attachment to chitosan. The benefit of chitosan functionalization with respect to its intrinsic antioxidant properties was finally evaluated in the present study. Interestingly, an increase of up to 90 % of the antioxidant activity of chitosan was observed.

Mots clés: Antioxidant Chitosan film Grafting Biosourced material Peptoid Polysaccharide

Domaines: Chimie

P-H. Elchinger, C. Delattre, S. Faure, O. Roy, S. Badel, et al.. Antioxidant activities of peptoid-grafted chitosan films.. Applied Biochemistry and Biotechnology, 2017, 181, pp.283-293. ⟨10.1007/s12010-016-2212-7⟩. ⟨hal-01526105⟩