Stability of real-time MR temperature mapping in healthy and diseased human liver

Abstract : Purpose: To determine the stability and quality of MR temperature mapping using the proton resonance frequency (PRF) method in the liver of hepatic tumor patients. Material and Methods: The standard deviation of a series of temperature maps was determined in 30 patients (21 cirrhotic livers with carcinoma, 9 non-cirrhotic livers with metastasis or angioma) and in 5 volunteers at normal body temperature under free breathing. A respiratory-gated segmented EPI sequence (3 slices in 1 expiration phase) was performed with SENSE acceleration on a 1.5 T scanner. Motion corrupted images were identified by calculation of the cross-correlation coefficient and discarded. Results: A T 2* range of 10-33 ms was found with especially low values in advanced cirrhotic livers. The mean temperature standard deviation in patients was 2.3°C (range 1.5-5.0°C). The stability in healthy livers was slightly better than that in cirrhotic livers, and it was higher in the right than in the left liver. The gaiting failed in 4 % of the images when the respiratory cycle was irregular, leading to motion artifacts and errors in the temperature maps. Conclusion: The achieved temperature stability and image quality makes real-time quantitative monitoring of thermal ablation of liver tumors feasible on a clinical scanner.
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Contributeur : Baudouin Denis de Senneville <>
Soumis le : vendredi 7 avril 2017 - 16:59:24
Dernière modification le : jeudi 7 février 2019 - 17:51:22
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Claudia Weidensteiner, Noureddine Kerioui, Bruno Quesson, Baudouin Denis de Senneville, Hervé Trillaud, et al.. Stability of real-time MR temperature mapping in healthy and diseased human liver. Journal of Magnetic Resonance Imaging, Wiley-Blackwell, 2004, 19 (4), pp.438-446. 〈10.1002/jmri.20019〉. 〈hal-01503864〉



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