Skip to Main content Skip to Navigation
Conference papers

Comparison of viscoelastic property characterization of plastisol phantoms with magnetic resonance elastography and high-frequency rheometry

P. Lefebvre 1 K. Tse Ve Koon 1 E. Brusseau 2 S. Nicolle 3 J.-F. Pallierne 4 Simon A. Lambert 1 D. Grenier 1, 5
1 RMN et optique : De la mesure au biomarqueur
CREATIS - Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé
2 Imagerie Ultrasonore
CREATIS - Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé
5 PILoT - Plateforme d'Imagerie Multimodale LyonTech
CREATIS - Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé
Abstract : This study aims at evaluating Magnetic Resonance Elastography (MRE) as a reliable technique for the characterization of viscoelastic properties of soft tissues. Three phantoms with different concentrations of plastisol and softener were prepared in order to mechanically mimic a broad panel of healthy and pathological soft tissues. Once placed in a MRI device, each sample was excited by a homemade external driver, inducing shear waves within the medium. The storage (G') and loss (G") moduli of each phantom were then reconstructed from MRE acquisitions over a frequency range from 300 to 1,000 Hz, by applying a 2D Helmholtz inversion algorithm. At the same time, mechanical tests were performed on four samples of each phantom with a High-Frequency piezo-Rheometer (HFR) over an overlapping frequency range (from 160 to 630 Hz) with the same test conditions (temperature, ageing). The comparison between both techniques shows a good agreement in the measurement of the storage and loss moduli, underlying the capability of MRE to noninvasively assess the complex shear modulus G* of a medium and its interest for investigating the viscoelastic properties of living tissues. Moreover, the phantoms with varying concentrations of plastisol used in this study show interesting rheological properties, which make them good candidates to simulate the broad variety of viscoelastic behaviors of healthy and pathological soft tissues.
Complete list of metadatas

https://hal.archives-ouvertes.fr/hal-01486826
Contributor : Béatrice Rayet <>
Submitted on : Friday, March 10, 2017 - 2:51:22 PM
Last modification on : Monday, February 10, 2020 - 3:34:41 PM

Identifiers

Citation

P. Lefebvre, K. Tse Ve Koon, E. Brusseau, S. Nicolle, J.-F. Pallierne, et al.. Comparison of viscoelastic property characterization of plastisol phantoms with magnetic resonance elastography and high-frequency rheometry. 38th IEEE Annual International Conference of the Engineering in Medicine and Biology Society (EMBC) 2016, Aug 2016, Orlando, United States. ⟨10.1109/EMBC.2016.7590924⟩. ⟨hal-01486826⟩

Share

Metrics

Record views

296