Hepatocellular Nuclear Factor 4 alpha (HNF-4 alpha) activation by saRNA rescues dyslipidemia and promotes favorable metabolic profile in a high fat diet (HFD) fed rat model.

Vikash Reebye , Kai-Wen Huang , Katherine Czysz , Simona Ciriello , Stehpanie Dorman , Isabella Reccia , H. S. Lai , Ling Peng (1) , Nikos Kostomitsopoulos , Joanna Nicholls , Robert Habib (2, 3) , Donald Tomalia , Pal Saetrom , Edmund Wilkes , Pedro Cutillas , John Rossi , Nagy Habib (4)

1 CINaM - Centre Interdisciplinaire de Nanoscience de Marseille
2 PSH - Unité de recherche Plantes et Systèmes de Culture Horticoles
3 Cirad-PERSYST - Département Performances des systèmes de production et de transformation tropicaux
4 Department of Surgical Oncology and Technology [London]

no abstract

Domaines: Biophysique

Vikash Reebye, Kai-Wen Huang, Katherine Czysz, Simona Ciriello, Stehpanie Dorman, et al.. Hepatocellular Nuclear Factor 4 alpha (HNF-4 alpha) activation by saRNA rescues dyslipidemia and promotes favorable metabolic profile in a high fat diet (HFD) fed rat model.. Hepatology, 2016, 63 (1 SUPP), pp.794A. ⟨10.1002/hep.28799⟩. ⟨hal-01452675⟩