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Article Dans Une Revue Biophysical Journal Année : 2016

Membrane Mediated Cooperativity Facilitates Cadherin Clustering in Model Membranes

Susanne Fenz
  • Fonction : Auteur
Timo Bihr
  • Fonction : Auteur
Rudolf Merkel
  • Fonction : Auteur
Ana-Suncana Smith
  • Fonction : Auteur

Résumé

Cadherins are major cell-cell adhesion molecules in vertebrate tissue. They play a vital role in the development and maintenance of multicellular organisms. Cadherins show homophilic as well as heterophilic binding to members of their subfamily with a relatively low 3D binding affinity. In order to establish stable adhesion a combination of trans and cis interactions has been postulated to promote oligomerization and junction formation

Domaines

Biophysique

Dates et versions

hal-01452673 , version 1 (02-02-2017)

Identifiants

Citer

Susanne Fenz, Timo Bihr, Daniel Schmidt, Rudolf Merkel, Kheya Sengupta, et al.. Membrane Mediated Cooperativity Facilitates Cadherin Clustering in Model Membranes. Biophysical Journal, 2016, 110 (3, 1), pp.190A. ⟨10.1016/j.bpj.2015.11.1058⟩. ⟨hal-01452673⟩
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