Skip to Main content Skip to Navigation
Journal articles

Brain Dynamics of Aging: Multiscale Variability of EEG Signals at Rest and during an Auditory Oddball Task(1,2,3)

Abstract : The present work focused on the study of fluctuations of cortical activity across time scales in young and older healthy adults. The main objective was to offer a comprehensive characterization of the changes of brain (cortical) signal variability during aging, and to make the link with known underlying structural, neurophysiological, and functional modifications, as well as aging theories. We analyzed electroencephalogram (EEG) data of young and elderly adults, which were collected at resting state and during an auditory oddball task. We used a wide battery of metrics that typically are separately applied in the literature, and we compared them with more specific ones that address their limits. Our procedure aimed to overcome some of the methodological limitations of earlier studies and verify whether previous findings can be reproduced and extended to different experimental conditions. In both rest and task conditions, our results mainly revealed that EEG signals presented systematic age-related changes that were time-scale-dependent with regard to the structure of fluctuations (complexity) but not with regard to their magnitude. Namely, compared with young adults, the cortical fluctuations of the elderly were more complex at shorter time scales, but less complex at longer scales, although always showing a lower variance. Additionally, the elderly showed signs of spatial, as well as between, experimental conditions dedifferentiation. By integrating these so far isolated findings across time scales, metrics, and conditions, the present study offers an overview of age-related changes in the fluctuation electrocortical activity while making the link with underlying brain dynamics.
Document type :
Journal articles
Complete list of metadata

Cited literature [26 references]  Display  Hide  Download

https://hal.archives-ouvertes.fr/hal-01450701
Contributor : Rita Sleimen-Malkoun <>
Submitted on : Monday, June 25, 2018 - 5:23:33 PM
Last modification on : Thursday, April 1, 2021 - 4:44:05 PM
Long-term archiving on: : Wednesday, September 26, 2018 - 2:21:57 PM

File

ENEURO.0067-14.2015.full.pdf
Publication funded by an institution

Licence


Distributed under a Creative Commons Attribution 4.0 International License

Identifiers

Collections

Citation

Rita Sleimen-Malkoun, Dionysios Perdikis, Viktor Müller, Jean-Luc Blanc, Raoul Huys, et al.. Brain Dynamics of Aging: Multiscale Variability of EEG Signals at Rest and during an Auditory Oddball Task(1,2,3). eNeuro, Society for Neuroscience, 2015, 2 (3), pp.ENEURO.0067--14.2015. ⟨10.1523/ENEURO.0067-14.2015⟩. ⟨hal-01450701⟩

Share

Metrics

Record views

369

Files downloads

268