The evolution of innate lymphoid cells

Eric Vivier (1) , Serge A. van De Pavert (1) , Max D. Cooper , Gabrielle T. Belz

1 CIML - Centre d'Immunologie de Marseille - Luminy

Innate lymphoid cells (ILCs) are the most recently discovered group of immune cells. Understanding their biology poses many challenges. We discuss here the current knowledge on the appearance of ILC subsets during evolution and propose how the connection between ILCs and T cells contributes to the robustness of immunity and hence to the fitness of the hosts.

Domaines: Immunologie

Eric Vivier, Serge A. van De Pavert, Max D. Cooper, Gabrielle T. Belz. The evolution of innate lymphoid cells. Nature Immunology, 2016, 17 (7), pp.790-794. ⟨10.1038/ni.3459⟩. ⟨hal-01438153⟩