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Phylogenetic and functional analysis of Aspergillus fumigatus MGTC, a fungal protein homologous to a bacterial virulence factor

Abstract :

MgtC is important for the survival of several bacterial pathogens in macrophages and for growth under magnesium limitation. Among eukaryotes, a gene homologous to mgtC was found only in the pathogenic fungus Aspergillus fumigatus. Our data show that the A. fumigatus MgtC (AfuMgtC) protein does not have the same function as the bacterial MgtC proteins.

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https://hal.archives-ouvertes.fr/hal-01389313
Contributor : Okina Université d'Angers <>
Submitted on : Friday, October 28, 2016 - 11:47:10 AM
Last modification on : Thursday, May 28, 2020 - 12:58:02 PM

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Amandine Gastebois, Anne-Beatrice Potard, Simonetta Gribaldo, Rémi Beau, Jean-Paul Latgé, et al.. Phylogenetic and functional analysis of Aspergillus fumigatus MGTC, a fungal protein homologous to a bacterial virulence factor. Applied and Environmental Microbiology, American Society for Microbiology, 2011, 77 (13), pp.4700-4703. ⟨10.1128/AEM.00243-11⟩. ⟨hal-01389313⟩

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