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Communication Dans Un Congrès Année : 2016

Groupwise Structural Parcellation of the Cortex: A Sound Approach Based on Logistic Models

Résumé

Current theories hold that brain function is highly related with long-range physical connections through axonal bundles, namely extrinsic connectivity. However, obtaining a groupwise cortical parcella-tion based on extrinsic connectivity remains challenging. Current par-cellation methods are computationally expensive; need tuning of several parameters or rely on ad-hoc constraints. Furthermore, none of these methods present a model for the cortical extrinsic connectivity. To tackle these problems, we propose a parsimonious model for the extrinsic con-nectivity and an efficient parcellation technique based on clustering of tractograms. Our technique allows the creation of single subject and groupwise parcellations of the whole cortex. The parcellations obtained with our technique are in agreement with anatomical and functional par-cellations in the literature. In particular, the motor and sensory cortex are subdivided in agreement with the human homunculus of Penfield. We illustrate this by comparing our resulting parcels with an anatomical atlas and the motor strip mapping included in the Human Connectome Project data.
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hal-01358436 , version 1 (31-08-2016)

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Guillermo Gallardo, Rutger H.J. Fick, William Wells Ill, Rachid Deriche, Demian Wassermann. Groupwise Structural Parcellation of the Cortex: A Sound Approach Based on Logistic Models. CDMRI 2016, Oct 2016, Athens, Greece. ⟨10.1007/978-3-319-54130-3_8⟩. ⟨hal-01358436⟩
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