Skip to Main content Skip to Navigation
Journal articles

Use of Adult Stem Cells for Cartilage Tissue Engineering: Current Status and Future Developments

Abstract : Due to their low self-repair ability, cartilage defects that result from joint injury, aging, or osteoarthritis, are the most often irreversible and are a major cause of joint pain and chronic disability. So, in recent years, researchers and surgeons have been working hard to elaborate cartilage repair interventions for patients who suffer from cartilage damage. However, current methods do not perfectly restore hyaline cartilage and may lead to the apparition of fibro- or hypertrophic cartilage. In the next years, the development of new strategies using adult stem cells, in scaffolds, with supplementation of culture medium and/or culture in low oxygen tension should improve the quality of neoformed cartilage. Through these solutions, some of the latest technologies start to bring very promising results in repairing cartilage from traumatic injury or chondropathies. This review discusses the current knowledge about the use of adult stem cells in the context of cartilage tissue engineering and presents clinical trials in progress, as well as in the future, especially in the field of bioprinting stem cells.
Document type :
Journal articles
Complete list of metadata

Cited literature [87 references]  Display  Hide  Download
Contributor : Catherine Baugé Connect in order to contact the contributor
Submitted on : Thursday, August 29, 2019 - 9:17:59 PM
Last modification on : Thursday, December 3, 2020 - 6:48:37 PM


2015 Bauge revue stem cell.pdf
Publisher files allowed on an open archive



Catherine Baugé, Karim Boumediene. Use of Adult Stem Cells for Cartilage Tissue Engineering: Current Status and Future Developments. Stem Cells International, Hindawi Publishing Corporation, 2015, 2015 (2015), pp.438026. ⟨10.1155/2015/438026⟩. ⟨hal-01354103⟩



Record views


Files downloads