B. Anlar and A. Gunel-ozcan, Tenascin-R: Role in the central nervous system, The International Journal of Biochemistry & Cell Biology, vol.44, issue.9, pp.1385-1389, 2012.
DOI : 10.1016/j.biocel.2012.05.009

A. Bé and R. Gilmer, A zoogeographic and taxonomic review of euthecosomatous pteropoda, Oceanic Micropaleontology. (ed Ramsey ATS) pp Page, 1977.

N. Bednar?ek, R. Feely, J. Reum, B. Peterson, J. Menkel et al., Limacina helicina shell dissolution as an indicator of declining habitat suitability owing to ocean acidification in the California Current Ecosystem, Proceedings of the Royal Society of London B: Biological Sciences, p.281, 2014.

N. Bednar?ek, J. Mo?ina, M. Vogt, O. Brien, C. Tarling et al., The global distribution of pteropods and their contribution to carbonate and carbon biomass in the modern ocean, Earth System Science Data, vol.4, issue.1, pp.167-186, 2012.
DOI : 10.5194/essd-4-167-2012

N. Bednar?ek and M. Ohman, Changes in pteropod distributions and shell dissolution across a frontal system in the California Current System, Marine Ecology Progress Series, vol.523, pp.93-103, 2015.
DOI : 10.3354/meps11199

N. Bednar?ek, G. Tarling, and D. Bakker, Extensive dissolution of live pteropods in the Southern Ocean, Nature Geoscience, vol.59, issue.6, pp.881-885, 2012.
DOI : 10.1111/j.1365-2486.2012.02668.x

M. Briffa, K. De-la-haye, and P. Munday, High CO2 and marine animal behaviour: Potential mechanisms and ecological consequences, Marine Pollution Bulletin, vol.64, issue.8, pp.1519-1528, 2012.
DOI : 10.1016/j.marpolbul.2012.05.032

X. Chen, G. Polleichtner, I. Kadurin, and S. Gründer, Zebrafish Acid-sensing Ion Channel (ASIC) 4, Characterization of Homo- and Heteromeric Channels, and Identification of Regions Important for Activation by H+, Journal of Biological Chemistry, vol.282, issue.42, pp.30406-30413, 2007.
DOI : 10.1074/jbc.M702229200

D. Chivers, M. Mccormick, and G. Nilsson, : a consequence of neurotransmitter interference, Global Change Biology, vol.366, issue.2, pp.515-522, 2014.
DOI : 10.1111/gcb.12291

J. Clements and H. Hunt, Marine animal behaviour in a high CO2 ocean, Marine Ecology Progress Series, vol.536, pp.259-279, 2015.
DOI : 10.3354/meps11426

S. Comeau, S. Alliouane, and J. Gattuso, Effects of ocean acidification on overwintering juvenile Arctic pteropods Limacina helicina, Marine Ecology Progress Series, vol.456, pp.279-284, 2012.
DOI : 10.3354/meps09696

S. Comeau, J. Gattuso, R. Jeffree, and F. Gazeau, Effect of carbonate chemistry manipulations on calcification, respiration, and excretion of a Mediterranean pteropod, Biogeosciences Discussions, vol.9, issue.5, pp.6169-6189, 2012.
DOI : 10.5194/bgd-9-6169-2012-supplement

S. Comeau, G. Gorsky, S. Alliouane, and J. Gattuso, Larvae of the pteropod Cavolinia inflexa exposed to aragonite undersaturation are viable but shell-less, Marine Biology, vol.326, issue.10, pp.2341-2345, 2010.
DOI : 10.1007/s00227-010-1493-6

S. Comeau, G. Gorsky, R. Jeffree, J. Teyssié, and J. Gattuso, Impact of ocean acidification on a key Arctic pelagic mollusc (<i>Limacina helicina</i>), Biogeosciences, vol.6, issue.9, pp.1877-1882, 2009.
DOI : 10.5194/bg-6-1877-2009-supplement

S. Comeau, R. Jeffree, J. Teyssié, and J. Gattuso, Response of the Arctic Pteropod Limacina helicina to Projected Future Environmental Conditions, PLoS ONE, vol.8, issue.6, p.11362, 2010.
DOI : 10.1371/journal.pone.0011362.s006

A. Conesa, S. Gotz, J. Garcia-gomez, J. Terol, M. Talon et al., Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research, Bioinformatics, vol.21, issue.18, pp.3674-3676, 2005.
DOI : 10.1093/bioinformatics/bti610

A. Dickson, Standard potential of the reaction: AgCl(s) + 1/2H 2 (g) = Ag(s) + HCl(aq), and and the standard acidity constant of the ion HSO 4 ? in synthetic sea water from 273, pp.113-127, 1990.

A. Dickson, C. Sabine, and J. Christian, Guide to best practices for ocean CO 2 measurements, PICES Special Publication, vol.3, 2007.

K. Drickamer, C-type lectin-like domains, Current Opinion in Structural Biology, vol.9, issue.5, pp.585-590, 1999.
DOI : 10.1016/S0959-440X(99)00009-3

E. Eden, N. Geva-zatorsky, and I. Issaeva, Proteome Half-Life Dynamics in Living Human Cells, Science, vol.331, issue.6018, pp.764-768, 2011.
DOI : 10.1126/science.1199784

R. Edgar, M. Domrachev, and A. Lash, Gene Expression Omnibus: NCBI gene expression and hybridization array data repository, Nucleic Acids Research, vol.30, issue.1, pp.207-210, 2002.
DOI : 10.1093/nar/30.1.207

B. Foster and J. Montgomery, Planktivory in benthic nototheniid fish in McMurdo Sound, Antarctica, Environmental Biology of Fishes, vol.3, issue.3, pp.313-318, 1993.
DOI : 10.1007/BF00001727

L. Fu, B. Niu, Z. Zhu, S. Wu, and W. Li, CD-HIT: accelerated for clustering the next-generation sequencing data, Bioinformatics, vol.28, issue.23, pp.3150-3152, 2012.
DOI : 10.1093/bioinformatics/bts565

F. Gazeau, L. Parker, and S. Comeau, Impacts of ocean acidification on marine shelled molluscs, Marine Biology, vol.29, issue.371, pp.2207-2245, 2013.
DOI : 10.1007/s00227-013-2219-3
URL : https://hal.archives-ouvertes.fr/hal-01255951

M. Grabherr, B. Haas, and M. Yassour, Full-length transcriptome assembly from RNA-Seq data without a reference genome, Nature Biotechnology, vol.30, issue.7, pp.644-652, 2011.
DOI : 10.1101/GR.229202. ARTICLE PUBLISHED ONLINE BEFORE MARCH 2002

M. Guppy and P. Withers, Metabolic depression in animals: physiological perspectives and biochemical generalizations, Biological Reviews, vol.28, issue.Dec., pp.1-40, 1999.
DOI : 10.1111/j.1469-185X.1999.tb00180.x

T. Hamilton, A. Holcombe, and M. Tresguerres, CO 2 -induced ocean acidification increases anxiety in Rockfish via alteration of GABA A receptor functioning, Proceedings of the Royal Society of London B: Biological Sciences, vol.281, 2014.

R. Heuer and M. Grosell, Physiological impacts of elevated carbon dioxide and ocean acidification on fish, AJP: Regulatory, Integrative and Comparative Physiology, vol.307, issue.9, pp.1061-1084, 2014.
DOI : 10.1152/ajpregu.00064.2014

E. Howes, N. Bednar?ek, and J. Büdenbender, Sink and swim: a status review of thecosome pteropod culture techniques, Journal of Plankton Research, vol.36, issue.2, 2014.
DOI : 10.1093/plankt/fbu002

T. Kobayashi, S. Shimabukuro-demoto, and R. Yoshida-sugitani, The Histidine Transporter SLC15A4 Coordinates mTOR-Dependent Inflammatory Responses and Pathogenic Antibody Production, Immunity, vol.41, issue.3, pp.375-388, 2014.
DOI : 10.1016/j.immuni.2014.08.011

H. Koh, J. Lee, S. Han, H. Park, S. Shin et al., A transcriptomic analysis of the response of the arctic pteropod Limacina helicina to carbon dioxide-driven seawater acidification, Polar Biology, vol.48, issue.Suppl 1, pp.1727-1740, 2015.
DOI : 10.1007/s00300-015-1738-4

K. Kwast and S. Hand, Acute depression of mitochondrial protein synthesis during anoxia: contributions of oxygen sensing, matrix acidification, and redox state, Journal of Biological Chemistry, vol.271, pp.7313-7319, 1996.

F. Lai, F. Jutfelt, and G. Nilsson, Altered neurotransmitter function in CO 2 -exposed stickleback (Gasterosteus aculeatus): a temperate model species for ocean acidification research, Conservation Physiology, vol.3, p.18, 2015.

N. Lambert and L. Grover, The mechanism of biphasic GABA responses, Science, vol.269, issue.5226, pp.928-929, 1995.
DOI : 10.1126/science.7638614

B. Langmead and S. Salzberg, Fast gapped-read alignment with Bowtie 2, Nature Methods, vol.9, issue.4, pp.357-359, 2012.
DOI : 10.1093/bioinformatics/btp352

H. Lavigne and J. Gattuso, Seacarb 1.2.3., an R package to calculate parameters of the seawater carbonate system, 2013.

S. Lévi, S. Logan, K. Tovar, and A. Craig, Gephyrin Is Critical for Glycine Receptor Clustering But Not for the Formation of Functional GABAergic Synapses in Hippocampal Neurons, Journal of Neuroscience, vol.24, issue.1, pp.207-217, 2004.
DOI : 10.1523/JNEUROSCI.1661-03.2004

M. Lindinger, D. Lauren, and D. Mcdonald, Acid-base balance in the sea mussel, Mytilus edulis. III. Effects of environmental hpercapnia on intra-and extracellular acid-base balance, Marine Biology Letters, vol.5, pp.371-381, 1984.

S. Lischka, J. Büdenbender, T. Boxhammer, and U. Riebesell, Impact of ocean acidification and elevated temperatures on early juveniles of the polar shelled pteropod <i>Limacina helicina</i>: mortality, shell degradation, and shell growth, Biogeosciences, vol.8, issue.4, pp.919-932, 2011.
DOI : 10.5194/bg-8-919-2011-supplement

S. Lischka and U. Riebesell, Synergistic effects of ocean acidification and warming on overwintering pteropods in the Arctic, Global Change Biology, vol.326, issue.12, pp.3517-3528, 2012.
DOI : 10.1111/gcb.12020

T. Lueker, A. Dickson, and C. Keeling, Ocean pCO2 calculated from dissolved inorganic carbon, alkalinity, and equations for K1 and K2: validation based on laboratory measurements of CO2 in gas and seawater at equilibrium, Marine Chemistry, vol.70, issue.1-3, pp.105-119, 2000.
DOI : 10.1016/S0304-4203(00)00022-0

A. Maas, G. Lawson, and A. Tarrant, Transcriptome-wide analysis of the response of the thecosome pteropod Clio pyramidata to short-term CO2 exposure, Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, vol.16, pp.1-9, 2015.
DOI : 10.1016/j.cbd.2015.06.002

A. Maas, K. Wishner, and B. Seibel, The metabolic response of pteropods to acidification reflects natural CO<sub>2</sub>-exposure in oxygen minimum zones, Biogeosciences, vol.9, issue.2, pp.747-757, 2012.
DOI : 10.5194/bg-9-747-2012

K. Mann and F. Siedler, Ostrich (Struthio camelus) eggshell matrix contains two different C-type lectin-like proteins. Isolation, amino acid sequence, and posttranslational modifications, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, vol.1696, issue.1, pp.41-50, 2004.
DOI : 10.1016/j.bbapap.2003.09.006

K. Mann, I. Weiss, S. André, H. Gabius, and M. Fritz, The amino-acid sequence of the abalone (Haliotis laevigata) nacre protein perlucin, European Journal of Biochemistry, vol.177, issue.16, pp.5257-5264, 2000.
DOI : 10.1046/j.1432-1327.2000.01602.x

C. Manno, N. Morata, and R. Primicerio, Limacina retroversa's response to combined effects of ocean acidification and sea water freshening, Estuarine, Coastal and Shelf Science, vol.113, pp.163-171, 2012.
DOI : 10.1016/j.ecss.2012.07.019

S. Martin, S. Richier, and M. Pedrotti, Early development and molecular plasticity in the Mediterranean sea urchin Paracentrotus lividus exposed to CO2-driven acidification, Journal of Experimental Biology, vol.214, issue.8, pp.1357-1368, 2011.
DOI : 10.1242/jeb.051169
URL : https://hal.archives-ouvertes.fr/hal-01255970

F. Melzner, M. Gutowska, and M. Langenbuch, Physiological basis for high CO 2 tolerance in marine ectothermic animals: pre-adaptation through lifestyle and ontogeny? Biogeosciences, pp.2313-2331, 2009.

B. Michaelidis, C. Ouzounis, A. Paleras, and H. Pörtner, Effects of long-term moderate hypercapnia on acid-base balance and growth rate in marine mussels Mytilus galloprovincialis, Marine Ecology Progress Series, vol.293, pp.109-118, 2005.
DOI : 10.3354/meps293109

A. Moya, L. Huisman, and E. Ball, -driven Acidification during the Initiation of Calcification, Molecular Ecology, vol.221, issue.10, pp.2440-2454, 2012.
DOI : 10.1111/j.1365-294X.2012.05554.x
URL : https://hal.archives-ouvertes.fr/hal-00109528

A. Moya, L. Huisman, S. Forêt, J. Gattuso, D. Hayward et al., -mediated acidification by upregulation of heat shock protein and Bcl-2 genes, Molecular Ecology, vol.11, issue.2, pp.438-452, 2015.
DOI : 10.1111/mec.13021
URL : https://hal.archives-ouvertes.fr/hal-00109528

G. Nilsson, D. Dixson, P. Domenici, M. Mccormick, C. Sorensen et al., Near-future carbon dioxide levels alter fish??behaviour by interfering??with neurotransmitter function, Nature Climate Change, vol.65, issue.3, pp.201-204, 2012.
DOI : 10.1098/rsbl.2009.0904

O. Donnell, M. Todgham, A. Sewell, and M. , Ocean acidification alters skeletogenesis and gene expression in larval sea urchins, Marine Ecology Progress Series, vol.398, pp.157-171, 2010.
DOI : 10.3354/meps08346

J. Orr, V. Fabry, and O. Aumont, Anthropogenic ocean acidification over the twenty-first century and its impact on calcifying organisms, Nature, vol.437, issue.7059, pp.681-686, 2005.
DOI : 10.1038/nature04095
URL : https://hal.archives-ouvertes.fr/hal-00124807

S. Pastorekova, S. Parkkila, J. Pastorek, and C. Supuran, Review Article, Journal of Enzyme Inhibition and Medicinal Chemistry, vol.98, issue.3, pp.199-229, 2004.
DOI : 10.1021/bi001416s

F. Perez and F. Fraga, Association constant of fluoride and hydrogen ions in seawater, Marine Chemistry, vol.21, issue.2, pp.161-168, 1987.
DOI : 10.1016/0304-4203(87)90036-3

P. Pesheva and R. Probstmeier, The yin and yang of tenascin-R in CNS development and pathology, Progress in Neurobiology, vol.61, issue.5, pp.465-493, 2000.
DOI : 10.1016/S0301-0082(99)00061-1

H. Pörtner, Ecosystem effects of ocean acidification in times of ocean warming: a physiologist???s view, Marine Ecology Progress Series, vol.373, pp.203-217, 2008.
DOI : 10.3354/meps07768

M. Prasad, W. Butler, and C. Qin, Dentin sialophosphoprotein in biomineralization, Connective Tissue Research, vol.115, issue.5, pp.404-417, 2010.
DOI : 10.1016/j.matbio.2009.03.006

R. Development and C. Team, R: A language and environment for statistical computing, 2010.

J. Rampal, Les thécosomes (mollusques pélagiques) Systématique et évolution - Écologies et biogéographie Mediterranéennes, 1975.

J. Ries, Oceanography: A sea butterfly flaps its wings, Nature Geoscience, vol.5, issue.12, pp.845-846, 2012.
DOI : 10.1029/2001GB001722

M. Robinson, D. Mccarthy, and G. Smyth, edgeR: a Bioconductor package for differential expression analysis of digital gene expression data, Bioinformatics, vol.26, issue.1, pp.139-140, 2010.
DOI : 10.1093/bioinformatics/btp616

R. Rodolfo-metalpa, F. Houlbreque, and E. Tambutte, Coral and mollusc resistance to ocean acidification adversely affected by warming, Nature Climate Change, vol.122, issue.6, pp.308-312, 2011.
DOI : 10.1038/nclimate1200

H. Sadamoto, H. Takahashi, T. Okada, H. Kenmoku, M. Toyota et al., De Novo Sequencing and Transcriptome Analysis of the Central Nervous System of Mollusc Lymnaea stagnalis by Deep RNA Sequencing, PLoS ONE, vol.7, issue.8, p.42546, 2012.
DOI : 10.1371/journal.pone.0042546.s005

J. Sambrook and D. Russel, Molecular cloning : a laboratory manual, 2001.

B. Seibel, A. Maas, and H. Dierssen, Energetic Plasticity Underlies a Variable Response to Ocean Acidification in the Pteropod, Limacina helicina antarctica, PLoS ONE, vol.86, issue.4, p.30464, 2012.
DOI : 10.1371/journal.pone.0030464.t002

B. Seibel and P. Walsh, Biological impacts of deep-sea carbon dioxide injection inferred from indices of physiological performance, Journal of Experimental Biology, vol.206, issue.4, pp.641-650, 2003.
DOI : 10.1242/jeb.00141

C. Supuran, Carbonic Anhydrases An Overview, Current Pharmaceutical Design, vol.14, issue.7, pp.603-614, 2008.
DOI : 10.2174/138161208783877884

A. Todgham and G. Hofmann, Transcriptomic response of sea urchin larvae Strongylocentrotus purpuratus to CO2-driven seawater acidification, Journal of Experimental Biology, vol.212, issue.16, pp.2579-2594, 2009.
DOI : 10.1242/jeb.032540

S. Watson, S. Lefevre, M. Mccormick, P. Domenici, G. Nilsson et al., Marine mollusc predator-escape behaviour altered by near-future carbon dioxide levels, Proceedings of the Royal Society B: Biological Sciences, vol.8, issue.2, 2014.
DOI : 10.1006/nlme.1996.0015