Bioinspired nose devices and their potential application for non-invasive olfactory detection of pathologies

Edith Pajot (1) , Julien Daligault (1) , Karine Badonnel (1) , Aurélie Dewaele (1) , Marie-Annick Persuy (1) , Patrice Congar (1) , Nicolas Meunier (1, 2) , Christine Baly (1) , Roland Salesse (1) , Nadia Zine (3) , Abdellatif Baraket (3) , Abdelhamid Errachid (3) , Annalisa Calo (4) , Patrizia Iavicoli (4) , Marta Sanmarti-Espinal (4) , Nicole Jaffrezic-Renault (3) , Gabriel Gomila (4) , Josep Samitier (4)

1 NOeMI - Neurobiologie de l'Olfaction et Modélisation en Imagerie
2 UVSQ - Université de Versailles Saint-Quentin-en-Yvelines
3 ISA - Institut des Sciences Analytiques
4 lab. Nanobioenginyeria

This work was carried out in the framework of the European project BOND (Bioelectronic Olfactory Neuron Device, http://bondproject.org/) aimed at using ORs carried by nanoscale liposomes as sensing elements of an electrochemical array, for specifically detecting target odorants from complex odorant mixtures. This project has potential applications in medical diagnosis, but also in agroalimentary or cosmetics quality control, security, and environment.

Mots clés: olfactory receptors (ORs); single-cell RT-PCR; modeling; docking; nanovesicles

Domaines: Neurosciences [q-bio.NC]; Alimentation et Nutrition

Edith Pajot, Julien Daligault, Karine Badonnel, Aurélie Dewaele, Marie-Annick Persuy, et al.. Bioinspired nose devices and their potential application for non-invasive olfactory detection of pathologies. 15. International symposium on Olfaction and Electronic Nose, International Society for Olfaction and Chemical Sensing (ISOCS). INT., Jul 2013, Daegu, South Korea. ⟨hal-01344430⟩