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Salivary cortisol in early psychosis: New findings and meta-analysis

Abstract : Schizophrenia is a multifactorial disorder and environmental risk factors for it might contribute to hypothalamo–pituitary–adrenal axis (HPA) dysregulation. While increased cortisol levels have been reported in schizophrenia, as well as in early psychosis (compared to healthy controls), a crucial unresolved issue is whether elevated cortisol levels could be related to the distress of an emerging illness, rather than being specific to psychosis. Here, we report new findings from the first French cohort of young help-seekers (ICAAR) including ultra-high risk subjects (UHR), first-episode of psychosis (FEP) and non at-risk help seekers controls (HSC), followed by a meta-analysis of all available reports on salivary basal cortisol levels in early psychosis (UHR and FEP).
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Contributor : Yannick Morvan Connect in order to contact the contributor
Submitted on : Monday, May 9, 2016 - 10:39:46 AM
Last modification on : Friday, October 1, 2021 - 3:30:10 AM



B. Chaumette, O. Kebir, C. Mam-Lam-Fook, Y. Morvan, J. Bourgin, et al.. Salivary cortisol in early psychosis: New findings and meta-analysis. Psychoneuroendocrinology, Elsevier, 2016, 63, pp.262-70. ⟨10.1016/j.psyneuen.2015.10.007⟩. ⟨hal-01312810⟩



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