Interval estimation of sequestered infected erythrocytes in malaria patients

Kwassi Holali Degue (1) , Denis Efimov (2, 3) , Abderrahman Iggidr (4, 5)

1 Départment de Génie Electrique [Montreal]
2 CRIStAL - Centre de Recherche en Informatique, Signal et Automatique de Lille - UMR 9189
3 NON-A - Non-Asymptotic estimation for online systems
4 Inria Nancy - Grand Est
5 IECL - Institut Élie Cartan de Lorraine

The problem of estimation of sequestered parasites Plasmodium falciparum in malaria, based on measurements of circulating parasites, is addressed. It is assumed that all (death, transition, recruitment and infection) rates in the model of a patient are uncertain (just intervals of admissible values are given) and the measurements are subject to a bounded noise, then an interval observer is designed. Stability of the observer can be verified by a solution of LMI. The efficiency of the observer is demonstrated in simulation.

Domaines: Automatique / Robotique

Kwassi Holali Degue, Denis Efimov, Abderrahman Iggidr. Interval estimation of sequestered infected erythrocytes in malaria patients. European Control Conference (ECC16), Jun 2016, Aalborg, Denmark. ⟨hal-01295741⟩